检索规则说明:AND代表“并且”;OR代表“或者”;NOT代表“不包含”;(注意必须大写,运算符两边需空一格)
检 索 范 例 :范例一: (K=图书馆学 OR K=情报学) AND A=范并思 范例二:J=计算机应用与软件 AND (U=C++ OR U=Basic) NOT M=Visual
作 者:师绍敏 刘阳[2] 毛燕 崔学博 李倩[1] 季上 刘亚玲[1] SHI Shaomin;LIU Yang;MAO Yan;CUI Xuebo;LI Qian;JI Shang;LIU Yaling(Department of Dermatology,Third Hospital of Hebei Medical University,Shijiazhuang 050051,China;Department of Pathology,Hebei General Hospital,Shijiazhuang,China)
机构地区:[1]河北医科大学第三医院皮肤科,河北石家庄050051 [2]河北省人民医院病理科,河北石家庄050051
出 处:《临床皮肤科杂志》2025年第3期154-156,共3页Journal of Clinical Dermatology
基 金:河北省自然科学基金(H2022206446)。
摘 要:报告1例阴茎疣状癌。患者男,50岁。龟头红斑、丘疹伴疼痛3个月。皮肤科检查:龟头红斑、糜烂及菜花状丘疹,表面覆黄白色污浊角质。皮肤镜检查:白色无结构区、石榴籽状分隔的丘疹、线状或弹簧状血管、靶样毛囊开口以及灰白色角质物。皮损组织病理检查:鳞状细胞团块呈疣状增生,细胞具有异形性,可见角化不良细胞及角化珠,肿瘤突破基膜向下侵袭性生长,癌组织周围间质中有淋巴细胞及浆细胞浸润。免疫组化示P40、P53及P63表达均(+),增殖核抗原(Ki-67)30%(+)。诊断:阴茎疣状癌。治疗:阴茎部分切除术。A 50-year-old male presented with erythema and papules on the glans penis,accompanied by pain for three months.Dermatological examination revealed erythema,erosions,and cauliflower-shaped papules covered with yellowish-white keratosis on the glans.Dermoscopy showed a white unstructured area,pomegranate seed-like papules,linear or spring-like blood vessels,targetoid follicular orifices,and gray-white keratosis.Histopathological examination showed verrucous hyperplasia of squamous cells,with heterotypic cells,parakeratotic cells,and keratin pearls.The tumor exhibited invasive downward growth,breaking through the basement membrane,with lymphocytic and plasma cell infiltration in the stroma.Immunohistochemical staining showed positive expression of P40,P53,and P63,with Ki67 at 30%.A diagnosis was established as penile verrucous carcinoma,and partial penile amputation was performed.
正在载入数据...
正在载入数据...
正在载入数据...
正在载入数据...
正在载入数据...
正在载入数据...
正在载入数据...
正在链接到云南高校图书馆文献保障联盟下载...
云南高校图书馆联盟文献共享服务平台 版权所有©
您的IP:216.73.216.38