1例以发热、腹痛、黄疸为首发症状的川崎病报道并文献复习  

Kawasaki Disease with Fever,Abdominal Pain and Jaundice as the First Symptom:a Case Report and Literature Review

作　　者：黄宝仪 钟志珊 蔡雅雯 郭书宁 刘华[2,3] 许华 李宏贵[2,3] Huang Baoyi;Zhong Zhishan;Cai Yawen;Guo Shuning;Liu Hua;Xu Hua;Li Honggui(The First Clinical Medical School,Guangzhou University of Chinese Medicine,Guangzhou 510405,China;the First Affiliated Hospital of Guangzhou University of Chinese Medicine,Guangzhou 510405,China;Guangdong Clinical Research Academy of Chinese Medicine,Guangzhou 510405,China)

机构地区：[1]广州中医药大学第一临床医学院,广州510405 [2]广州中医药大学第一附属医院,广州510405 [3]广东省中医临床研究院,广州510405

出　　处：《儿科药学杂志》2025年第4期29-33,共5页Journal of Pediatric Pharmacy

基　　金：国家中医优势专科建设项目(儿科),国中医药医政函[2024]90号;广东省名中医传承工作室建设项目,粤中医办函[2023]108号;广州中医药大学教育科学研究基金-许华教学名师工作室,编号A1-2601-21。

摘　　要：患儿,男,7岁,因“发热、腹痛、黄疸、咳嗽”为主症入院,结合临床表现、辅助检查,诊断为川崎病(KD)、胆囊炎、肝功能异常、葡萄糖-6-磷酸脱氢酶(G6PD)缺乏症,予大剂量静脉用丙种球蛋白(IVIG)、口服氯吡格雷及其他对症支持治疗,随访预后佳。通过分析KD合并胆囊炎、肝功能异常的临床表现、发病机制、治疗等,加强临床对出现胃肠道症状的可疑KD患儿的识别和重视,并提出阿司匹林对于G6PD缺乏症的KD患儿的应用思考。A 7-year-old boy was admitted into the hospital with chief complaints of“fever,abdominal pain,jaundice,and cough”.After considering clinical manifestations and auxiliary examinations,the child was diagnosed with Kawasaki disease(KD),cholecystitis,abnormal liver function,and glucose-6-phosphate dehydrogenase(G6PD)deficiency.Patients were treated with high-dose intravenous immunoglobulin(IVIG),oral clopidogrel and other symptomatic supportive therapy.The prognosis was good at follow-up.This paper analyzes the clinical manifestations,pathogenesis,and treatment of KD combined with cholecystitis and liver function abnormalities to enhance clinical recognition and attention to children with suspected KD presenting with gastrointestinal symptoms,and raises considerations regarding the use of aspirin in children with KD and G6PD deficiency.

关 键 词：川崎病 胆囊炎 肝功能异常 葡萄糖-6-磷酸脱氢酶缺乏症 阿司匹林 儿童 

分 类 号：R725.4[医药卫生—儿科]