Ⅱ型神经纤维瘤病1例并文献复习  

Neurofibromatosis type 2:report of one case and literature review

作　　者：姚一焓 时金昭 甘强 王汉东 YAO Yihan;SHI Jinzhao;GAN Qiang;WANG Handong(Department of Neurosurgery,BenQ Hospital,Nanjing 210000,China)

机构地区：[1]南京明基医院神经外科,南京210000

出　　处：《临床神经外科杂志》2025年第2期233-236,共4页Journal of Clinical Neurosurgery

摘　　要：目的 报告一例Ⅱ型神经纤维瘤病患者及其治疗。方法 回顾性分析南京明基医院神经外科2023年8月收治的1例Ⅱ型神经纤维瘤病患者的临床资料,并对相关文献进行复习。结果 患者临床表现为左耳听力进行性下降、耳鸣及左侧面部肿胀。影像学检查结果显示患者体内多发散在病灶。该患者经多次手术之后治疗效果良好。结论 由于Ⅱ型神经纤维瘤病是常染色体显性遗传病,该类患者应做到早发现、早治疗及定期随访。该病的主要治疗方式是手术,但由于肿瘤可累及广泛,最终需多学科共同治疗。Objective To report a case of neurofibromatosis type 2 and its treatment.Methods The clinical data of a patient with neurofibromatosis type 2 admitted to the Department of Neurosurgery,Nanjing BenQ Hospital in August 2023 were analyzed retrospectively,and the related literatures were reviewed.Results The patient presented with progressive hearing loss of the left ear,tinnitus and left facial swelling.The imaging examination results show that multiple scattered lesions in the patient's body.The patient had a good therapeutic effect after multiple operations.Conclusions As neurofibromatosis type 2 is an autosomal dominant genetic disease,early detection,early treatment and regular follow-up should be done for this kind of patients.The main treatment for this disease is surgery,but due to the extensive involvement of tumors,multidisciplinary treatment is ultimately required.

关 键 词：Ⅱ型神经纤维瘤病 脑膜瘤 听神经瘤 

分 类 号：R739.41[医药卫生—肿瘤] R651[医药卫生—临床医学]