2022—2023年湖北省上消化道癌机会性筛查结果分析  

Analysis of Opportunistic Screening Results for Upper Gastrointestinal Cancer in Hubei Province from 2022 to2023

作　　者：庹吉妤 姚霜 秦宇 夏雅芬 孟繁地 张敏[1] TUO Jiyu;YAO Shuang;QIN Yu;XIA Yafen;MENG Fandi;ZHANG Min(Cancer Hospital Affiliated to Tongji Medical College,Huazhong University of Science and Technology/Hubei Cancer Hospital,Wuhan 430079,China)

机构地区：[1]华中科技大学同济医学院附属肿瘤医院/湖北省肿瘤医院,湖北武汉430079

出　　处：《中国肿瘤》2025年第4期272-278,共7页China Cancer

摘　　要：[目的]分析湖北省2022—2023年上消化道癌机会性筛查结果。[方法]整理湖北省2022年1月1日至2023年12月31日上消化道癌机会性筛查数据。计算活检率、阳性检出率和早诊率,并采用卡方检验和趋势卡方检验比较不同性别、年龄别、地区间率的差异。[结果]2022—2023年间,共纳入上消化道癌机会性筛查372 507人,其中100 379人进行了组织病理学检查,活检率为26.95%。共检出上消化道阳性病例(高级别上皮内瘤变+早期癌+中晚期癌)4 678例,阳性病变检出率为1.26%,食管、贲门、胃分部位阳性病变检出率分别为0.61%、0.07%和0.58%。其中,检出上消化道癌早期病例(高级别上皮内瘤变+早期癌)721例,早诊率为15.41%,食管、贲门、胃分部位的早诊率分别为14.53%、11.96%和16.89%。[结论]实施上消化道癌的机会性筛查有助于扩大癌症筛查的覆盖范围,需要进一步加强规范化、同质化的培训,完成高质量的内镜检查,以提高上消化道癌机会性筛查项目的检出率和早诊率。[Purpose] To analyze the opportunistic screening results of upper gastrointestinal cancer in Hubei Province from 2022 to 2023.[Methods] The data of upper gastrointestinal cancer opportunistic screening program in Hubei Province from January 1,2022 to December 31,2023were summarized.The biopsy rate,positive lesion detection rate and early diagnosis rate were analyzed.The differences in rates between/among different sexes,age groups and regions were compared by χ2test,trend χ2test.[Results] A total of 372 507 people were included in the opportunistic screening of upper gastrointestinal cancer from 2022 to 2023.Among them,100 379 individuals underwent biopsy histopathological examination,with a biopsy rate of 26.95%.A total of4 678 positive cases(high-grade intraepithelial neoplasia,early-stage cancer and advanced cancer) were detected in the opportunistic screening,with a positive lesion detection rate of 1.26%.The detection rates of positive lesion in the esophagus,cardia and stomach were 0.61%,0.07%and 0.58%,respectively.There were 721 cases of early upper gastrointestinal cancer(high-grade intraepithelial neoplasia,early-stage cancer),representing an early diagnosis rate of 15.41%.The early diagnosis rates for the esophagus,cardia and stomach were 14.53%,11.96% and 16.89%,respectively.[Conclusions] The implementation of opportunistic screening for upper gastrointestinal cancer is conducive to expanding the coverage of screening.It is necessary to strengthen standardized and homogeneous training and complete high-quality endoscopic examination to improve the detection rate and early diagnosis rate of opportunistic screening program for upper gastrointestinal cancer.

关 键 词：上消化道癌 机会性筛查 活检率 阳性检出率 湖北 

分 类 号：R73-31[医药卫生—肿瘤] R735[医药卫生—临床医学]