2016—2020年辽宁省肿瘤登记地区恶性肿瘤流行状况及2006—2020年趋势分析  

Cancer Incidence and Mortality in Liaoning Cancer Registration Areas from 2016 to 2020 and Trends from 2006 to 2020

作　　者：穆慧娟[1] 礼彦侠[1] 马祥[1] 那军[1] 于丽娅[1] 田疆[1] 刘莉[1] MU Huijuan;LI Yanxia;MA Xiang;NA Jun;YU Liya;TIAN Jiang;LIU Li(Liaoning Center for Disease Control and Prevention,Shenyang 110173,China)

机构地区：[1]辽宁省疾病预防控制中心,辽宁沈阳110173

出　　处：《中国肿瘤》2025年第4期279-289,共11页China Cancer

基　　金：辽宁省自然科学基金指导计划(20180550495)。

摘　　要：[目的]分析辽宁省肿瘤登记地区2016—2020年恶性肿瘤发病和死亡状况及2006—2020年流行趋势。[方法]收集2016—2020年辽宁省肿瘤登记地区上报的恶性肿瘤发病与死亡资料,计算发病与死亡粗率、标化率、累积率(0~74岁)和年龄别率等,标化率使用2000年中国人口(简称中标率)和Segi世界标准人口(简称世标率)年龄构成为标准分别进行计算;利用Joinpoint软件对发病、死亡趋势进行分析。[结果] 2016—2020年辽宁省肿瘤登记地区恶性肿瘤粗发病率为422.30/10万,中标率为215.67/10万,世标率为209.52/10万;城市发病中标率(225.00/10万)高于农村(190.15/10万),男性中标发病率(221.47/10万)高于女性(213.03/10万)。2016—2020年恶性肿瘤粗死亡率为254.22/10万,中标率为113.26/10万,世标率为112.91/10万,城市中标死亡率(113.12/10万)与农村(113.01/10万)基本持平,男性中标死亡率(146.86/10万)高于女性(83.46/10万)。肺癌发病(世标率为46.13/10万)和死亡(世标率为32.04/10万)均居辽宁省首位。2006—2020年城市恶性肿瘤粗发病率、中标率和世标率均为升高趋势(AAPC=3.921%,t=16.222,P <0.05;AAPC=0.823%,t=2.409,P <0.05;AAPC=0.875%,t=2.933,P<0.05);城市女性粗发病率、中标率和世标率均为升高趋势(AAPC=4.151%,t=15.888,P<0.05;AAPC=1.597%,t=4.819,P<0.05;AAPC=1.514%,t=4.752,P<0.05)。同期城市恶性肿瘤粗死亡率呈升高趋势(AAPC=3.175%,t=14.745,P<0.05),死亡世标率呈下降趋势(AAPC=-0.908%,t=-2.273,P<0.05);男、女性死亡率均为升高趋势(AAPC=3.010%,t=6.032,P<0.05;AAPC=2.820%,t=5.921,P<0.05),仅女性死亡中标率和世标率(AAPC=-1.487%,t=-2.437,P<0.05;AAPC=-2.680%,t=-2.246,P<0.05)的下降趋势有统计学意义。2016—2020年农村恶性肿瘤发病率、中标率和世标率变化趋势均无统计学意义,但男性发病率呈升高趋势(AAPC=2.025%,t=3.853,P<0.05)。同期农村恶性肿瘤粗死亡率升高(AAPC=3.577%,t=9.377,P<0.05),死亡中标率和世标率虽呈[Purpose] To analyze cancer incidence and mortality in Liaoning cancer registration areas from 2016 to 2020 and the trends from 2006 to 2020.[Methods] Cancer data in cancer registration areas in Liaoning Province from 2016 to 2020 were collected.Τhe incidence and mortality,age-standardized rate,cumulative rate(0 ~74 years old),and age-specific rate were calculated.Age-standardized incidence and mortality rate were calculated by the Chinese standard population(ASIRC,ASMRC) and Segi world standard population(ASIRW,ASMRW).Joinpoint software was applied to analyze the trends of incidence and mortality.[Results] From 2016 to 2020,the crude incidence rate of cancer in Liaoning cancer registration areas was 422.30/105,the ASIRC and ASIRW were 215.67/105and 209.52/105.The ASIRC was higher in urban areas(225.00/105)than that in rural areas(190.15/105),and higher in male(221.47/105) than that in female(213.03/105).The crude mortality rate was 254.22/105,the ASMRC and ASMRW were 113.26/105and 112.91/105.The ASMRC in urban areas(113.12/105) was the same as that in rural areas(113.01/105),and higher in male(146.86/105) than that in female(83.46/105).The ASIRW of lung cancer was 46.13/105,and the ASMRW was 32.04/105,both ranking the first of all cancers.From 2006 to 2020,the crude incidence,ASIRC and ASIRW in urban areas showed an increasing trend(AAPC=3.921%,t=16.222,P<0.05;AAPC=0.823%,t=2.409,P<0.05;AAPC =0.875%,t =2.933,P <0.05).The crude incidence,ASIRC and ASIRW in urban female were all rising(AAPC=4.151%,t=15.888,P<0.05;AAPC=1.597%,t=4.819,P<0.05;AAPC=1.514%,t=4.752,P<0.05).During the same period,the cancer mortality in urban areas showed an increasing trend(AAPC=3.175%,t=14.745,P<0.05),and the ASMRW showed a decreasing trend(AAPC=-0.908%,t=-2.273,P<0.05).The crude mortality of both men and women showed an increasing trend(AAPC =3.010%,t =6.032,P <0.05;AAPC=2.820%,t=5.921,P<0.05),while the crude mortality and ASMRW for female showed a significant downward trend(AAPC=-1.487%,t=-2.437,P<0.05;AAPC=-2.680%,t=-2.246,P<0.05).

关 键 词：恶性肿瘤 发病率 死亡率 趋势 辽宁 

分 类 号：R73-31[医药卫生—肿瘤]