基于一站式CT P联合CTA检查的脑血管畸形与脑灌注特征的研究  

Characteristics of Cerebral Vascular Malformation and Perfusion Evaluated by One-stop Cerebral CTP and CTA Examination

作　　者：杜颖 邓小飞[1] 郗艳 舒政[1] DU Ying;DENG Xiao-fei;XI Yan;SHU Zheng(Department of Radiology,Shanghai TCM-integrated Hospital,Shanghai 200082,China)

机构地区：[1]上海市中西医结合医院影像科,上海200082

出　　处：《中国CT和MRI杂志》2025年第4期36-38,共3页Chinese Journal of CT and MRI

基　　金：上海市虹口区卫生健康委员会医学科研课题计划(虹卫1801-04)。

摘　　要：目的通过一站式颅脑CTP联合CTA检查分析颅内血管畸形与脑实质灌注参数特征的关系。方法搜集2021年02月到2024年02月临床怀疑脑血管病并行颅脑一站式颅脑CT检查的患者,根据颅脑CTA筛选出脑血管畸形的患者,使用去卷积法分析得到灌注参数,测量脑血管畸形处的脑组织的CBF、CBV、MTT、TTD、TTS、Tmax和FED参数值,将相应对侧的灌注参数作为对照组。结果最终入组7例患者,重建CTA显示的静脉畸形3例,动静脉畸形4例,脑血管畸形侧CBF、CBV值较对侧的增高且差异具有统计学意义(P<0.001),CBF平均值分别为123.60±22.12和61.73±21.22,CBV平均值分别为7.01±0.88和3.79±1.12,MTT、TTD和TTS较对侧减低且差异具有统计学意义(P<0.05),但Tmax减低和FED增高的组间差异不具有统计学意义(P>0.05)。结论一站式CTP联合CTA检查同时诊断脑血管畸形和脑灌注异常,脑血管畸形附近的脑组织呈高灌注特征。Objective To evaluate the correlation between intracranial vascular malformation and cerebral perfusion parameters using one-stop CT perfusion(CTP)and CT angiography(CTA)examination.Methods Patients suspected of cerebrovascular diseases who received a one-stop cerebral examination from February 2021 to February 2024 were collected.Cerebrovascular malformations were detected utilizing CTA.Deconvolution analysis has been used to calculate perfusion parameters,and the CBF,CBV,MTT,TT D,TTS,Tmax,and FED parameters of brain at the location of cerebrovascular malformation were quantified.The contralateral side represents the control group.Results 7 patients were eventually enrolled in the study,with 3 suffering venous malformations and 4 with arteriovenous malformations.The cerebral blood flow(CBF)and cerebral blood volume(CBV)values on the side cerebral with vascular malformation were significantly higher than those on the opposite side,with a statistically significant difference(P<0.001).The average CBF values were 123.60±22.12 and 61.73±21.22,respectively,whereas the average CBV values were 7.01±0.88 and 3.79±1.12,respectively.The MTT,TT D,and TTS decreased compared to the contralateral side,and the difference was statistically significant(P<0.05),but the differences in Tmax and FED between the two groups were not statistically significant(P>0.05).Conclusion One-stop CTP and CTA examination can simultaneously diagnose the cerebral vascular malformation and cerebral perfusion abnormalities.The cerebral region surrounding the vascular malformation location emphasizes hyper-perfusion characteristics.

关 键 词：CT灌注 CT动脉成像 脑血管畸形 高灌注 

分 类 号：R743.4[医药卫生—神经病学与精神病学]