MRI动脉自旋标记和经颅多普勒超声测量静息脑血流动力学的研究  

A Study on Resting Cerebral Hemodynamics Measured by MRI Arterial Spin Labeling and Transcranial Doppler Ultrasound

作　　者：黄伟 范斌 李倩楠 尹安 王礼星 袁超[6] HUANG Wei;FAN Bin;LI Qian-nan;YIN An;WANG Li-xing;YUAN Chao(TCD Room,Ultrasound Medicine Department,Bao'an Central Hospital of Shenzhen,Shenzhen 518101,Guangdong Province,China;Department of Hepatobiliary Surgery,The First Affiliated Hospital of Air Force Medical University,Xi'an,Shaanxi 710000,China;Department of Health Examination,the First Affiliated Hospital of Northwest University(Xi'an NO.1 Hospital),Xi'an 710001,Shaanxi Province,China;Department of Training rehabilitation,Lintong Rehabilitation Center,Zhengzhou Joint Logistics Support Center of the People's Liberation Army of China Lintong 710600,Shaanxi Province,China;Department of Ultrasound,940 Hospital of the Joint Logistics Support Force of the People's Liberation Army of China,Lanzhou 730030,Gansu Province,China;Nanfang Hospital,Southern Medical University,Guangzhou 515000,Guangdong Province,China)

机构地区：[1]深圳市宝安区中心医院超声医学科TCD室,广东深圳518101 [2]空军军医大学第一附属医院肝胆外科,陕西西安710000 [3]西北大学附属第一医院(西安市第一医院)健康体检部,陕西西安710001 [4]中国人民解放军郑州联勤保障中心临潼康复疗养中心训练康复科,陕西临潼710600 [5]中国人民解放军联勤保障部队第九四〇医院超声科,甘肃兰州730030 [6]南方医科大学南方医院,广东广州515000

出　　处：《中国CT和MRI杂志》2025年第4期39-42,共4页Chinese Journal of CT and MRI

基　　金：2023年度广东省医学科学基金指令性课题题目(C2023066)。

摘　　要：目的评估MRI动脉自旋标记和经颅多普勒超声测量静息脑血流动力学价值。方法35名健康志愿者(青年组20人,老年组15人)完成两次实验(TCD/MRI)。评估了成像方式内和成像方式之间的老化和健康影响。结果与年轻受试者相比,老年受试者大脑中动脉血流速度(MCAV,TCD)降低,通过时间(MRI)减慢(P<0.05)。年轻组的灰质脑血流灌注(MRI)高于老年组,但差异不显著(P=0.13)。年轻组的运动效果与老年组相反。整个队列通过时间与MCAV相关(r=TCD0.63;P<0.05),而组织灌注量与−测量无关。结论TCD和MRI提供了互补的静息CBF测量,值得推广。Objective To evaluate the value of MRI arterial spin labeling and transcranial Doppler ultrasound in measuring resting cerebral hemodynamics.Methods 35 healthy volunteers(20 in the youth group and 15 in the elderly group)completed two experiments(TCD/MRI).Evaluated the aging and health impacts within and between imaging methods.Results Compared with young participants,the middle cerebral artery blood flow velocity(MCAV,TCD)of elderly participants decreased and slowed down over time(MRI)(P<0.05).The gray matter cerebral blood flow perfusion(MRI)of the young group was higher than that of the elderly group,but the difference was not significant(p=0.13).The exercise effect of the young group is opposite to that of the elderly group.The entire queue was correlated with MCAV over time(r=TCD0.63;P<0.05),while tissue perfusion was not related to measurement.Conclusion TCD and MRI provide complementary resting CBF measurements and are worth promoting.

关 键 词：MRI动脉自旋标记 经颅多普勒超声 静息脑血流动力学 

分 类 号：R730.41[医药卫生—肿瘤]