英夫利昔治疗克罗恩病致血细胞减少病例1例并文献复习  

A Case of Hemopenia Due to Infliximab Treatment of Crohn′s Disease and Literature Review

作　　者：黄奎 余学军 张姮[2] HUANG Kui;YU Xuejun;ZHANG Heng(School of Medicine,Jianghan University,Wuhan 430056,Hubei,China;Department of Gastroenterology,The Central Hospital of Wuhan,Wuhan 430014,Hubei,China)

机构地区：[1]江汉大学医学部,湖北武汉430056 [2]武汉市中心医院消化内科,湖北武汉430014

出　　处：《江汉大学学报(自然科学版)》2025年第2期64-70,共7页Journal of Jianghan University:Natural Science Edition

摘　　要：目的总结英夫利昔治疗以十二指肠为发病部位的克罗恩病(Crohn′s disease,CD)过程中的不良反应。方法回顾性分析1例使用英夫利昔治疗克罗恩病患者的临床资料并进行相关文献复习。结果患者在使用英夫利昔过程中出现不良反应,表现为血红蛋白和血小板的减少,通过调整治疗方案后,患者血小板和血红蛋白逐渐恢复正常。结论在临床工作中尽早识别英夫利昔治疗CD过程中可能出现的不良反应,提高对此疾病治疗的认知,为患者提供合理的治疗方案。Objective To summarize the adverse effects of infliximab in treating Crohn′s disease(CD)with duodenum as the site of onset.Methods We retrospectively analyzed the clinical data of one patient treated with infliximab for Crohn′s disease in the Central Hospital of Wuhan and conducted a relevant literature review.Results The patient experienced adverse reactions during the use of infliximab in the form of decreased hemoglobin and platelets,which gradually returned to normal by adjusting the treatment regimen.Conclusion We should early identify possible adverse reactions during the treatment of CD with infliximab,improve the knowledge of colleagues in treating this disease,and provide patients with reasonable treatment programs.

关 键 词：克罗恩病 英夫利昔单抗 不良反应 血红蛋白 血小板 

分 类 号：R574.5[医药卫生—消化系统]