眼睑黄色瘤的手术切除联合CO_(2)激光治疗作用及对复发率的影响  

The Effect of Surgical Resection Combined with CO_(2)Laser Treatment on Eyelid Xanthoma and Its Influence on Recurrence Rate

作　　者：孙嘉凯 SUN Jia-kai(Department of Ophthalmology,The Third Affiliated Hospital of Nanyang Medical College,Nanyang 473000,Henan Province,China)

机构地区：[1]南阳医学高等专科学校第三附属医院眼科,河南南阳473000

出　　处：《罕少疾病杂志》2025年第4期15-17,共3页Journal of Rare and Uncommon Diseases

摘　　要：目的探讨手术切除+二氧化碳(CO_(2))激光治疗眼睑黄色瘤的效果及复发情况。方法选择我院(2019年8月至2022年8月)收治的眼睑黄色瘤患者58例,以随机掷骰子法分为对照组与观察组,每组29例,对照组:手术切除治疗,观察组:手术切除联合CO_(2)激光治疗,对比两组治疗效果,瘢痕分级情况,不同时间(治疗后1、6个月)美容效果(残留瘤体评分、凹陷瘢痕评分、色素异常评分),不良反应发生率,治疗后6个月复发率。结果两组总有效率组间对比,观察组更高,P<0.05;与对照组比较,观察组瘢痕分级0级占比更高,2级占比更低,P<0.05;两组瘢痕分级1级、3级占比对比,P>0.05;治疗后1个月,两组患者残留瘤体评分、凹陷瘢痕评分、色素异常评分及总分对比,P>0.05;治疗后6个月,两组各项评分较术后1个月均明显降低,且观察组低于对照组,P<0.05;与对照组比较,观察组不良反应发生率无明显差异,P>0.05;治疗后6个月,与对照组比较,观察组复发率更低,P<0.05。结论对眼睑黄色瘤患者,采用手术、CO_(2)激光联合治疗具有更好的效果,瘢痕分级情况更优,可提高患者美容效果,且治疗后远期复发率低,不会明显增加不良反应。Objective To investigate the effect and recurrence of xanthoma of eyelid treated by CO_(2)laser.Methods Fifty-eight patients with xanthoma of eyelid admitted to our hospital from August 2019 to August 2022 were randomly divided into control group(n=29)and observation group(n=29).The control group underwent surgical resection,Observation Group on the basis of the control group combined with CO_(2)Laser.The therapeutic effect,SCAR grading,cosmetic effect(residual tumor score,depressed scar score,abnormal pigmentation score)and adverse reaction rate were compared between the two groups at different time(1,6 months after treatment),the recurrence rate was 6 months after treatment.Results The total effective rate of observation group was higher than that of control group,P<0.05.Compared with the control group,the ratio of grade 0 and Grade 2 was higher in the Observation Group,P<0.05;the ratio of Grade 1 and Grade 3 in the two groups,P>0.05;one month after treatment,the scores of residual tumor,depressed scar,abnormal pigmentation and total scores of the two groups were compared,P>0.05.After 6 months of treatment,the scores in both groups were significantly lower than that of 1 month after operation,and the scores in the observation group were lower than those in the control group,P<0.05;compared with the control group,there was no significant difference in the incidence of adverse reactions in the observation group,P>0.05.Compared with the control group,the recurrence rate was lower in the Observation Group(P<0.05).Conclusion Surgical resection combined with CO_(2)laser treatment for xanthoma of the eyelid has a significant effect,with better scar grading,improved cosmetic results,and a low long-term recurrence rate after treatment,without significantly increasing adverse reactions.

关 键 词：眼睑黄色瘤 手术切除 二氧化碳激光 复发率 美容效果 瘢痕分级 

分 类 号：R739.71[医药卫生—肿瘤]