术前脉冲光联合睑板腺按摩对白内障合并MGD患者的临床疗效  

Clinical Effect of Preoperative Pulsed Light Combined with Meibomian Gland Massage in the Treatment of Patients with Cataract Complicated with MGD

作　　者：刘芳 潘虹 李金颖 邹丹 LIU Fang;PAN Hong;LI Jinying;ZOU Dan(Eye Disease Center,Hongqi Hospital Affiliated to Mudanjiang Medical University,Mudanjiang 157000,China)

机构地区：[1]牡丹江医科大学附属红旗医院眼病中心,黑龙江牡丹江157000

出　　处：《中国医学创新》2025年第10期6-10,共5页Medical Innovation of China

基　　金：2021年度黑龙江省省属高等学校基本科研项目(2021-KYYWF-0492)。

摘　　要：目的:探究术前脉冲光联合睑板腺按摩对白内障合并睑板腺功能障碍(MGD)患者的临床疗效。方法:将2023年2月—2024年6月牡丹江医科大学附属红旗医院的100例白内障合并MGD患者根据随机数字表法分为两组。对照组(n=50)进行术前睑板腺按摩治疗,观察组(n=50)则进行术前脉冲光联合睑板腺按摩治疗。比较两组MGD治疗总有效率、治疗前后的睑板腺功能评分(排出能力评分、分泌物性状评分及萎缩评分)、眼表状态[眼表疾病指数量表(OSDI)]及生存质量[视功能损害眼病患者生存质量量表(SQOL-DVI)]。结果:观察组的MGD治疗总有效率显著高于对照组,差异有统计学意义(P<0.05),治疗前两组的睑板腺排出能力评分、分泌物性状评分及萎缩评分、OSDI评分及SQOL-DVI评分比较,差异均无统计学意义(P>0.05),术后1周及4周观察组的睑板腺排出能力评分、分泌物性状评分及萎缩评分、OSDI评分均显著低于对照组,SQOL-DVI评分均显著高于对照组,差异均有统计学意义(P<0.05)。结论:术前脉冲光联合睑板腺按摩对白内障合并MGD患者的临床疗效较好,有助于控制白内障手术对患者眼部状态的不良影响,对于相关生存质量的改善也有积极的作用。Objective:To investigate the clinical effect of preoperative pulsed light combined with meibomian gland massage in the treatment of patients with cataract complicated with meibomian gland dysfunction(MGD).Method:A total of 100 patients with cataract complicated with MGD from February 2023 to June 2024 in Hongqi Hospital Affiliated to Mudanjiang Medical University were divided into two groups according to the random number table method.The control group(n=50)was treated with preoperative meibomian gland massage,the observation group(n=50)was treated with preoperative pulsed light combined with meibomian gland massage.Then the total effective rates for MGD,meibomian gland function score(discharge ability score,secretion trait score,and atrophy score),ocular surface situation[ocular surface disease index(OSDI)]and life quality[scale of quality of life for disease with vision impairment(SQOL-DVI)]before and after the treatment of two groups were compared.Result:The total effective rate for MGD of observation group was significantly higher than that of control group,the difference was statistically significant(P<0.05),the discharge ability scores,secretion trait scores and atrophy scores,OSDI scores and SQOL-DVI scores of two groups before the treatment were compared,the differences were not statistically significant(P>0.05),the discharge ability score,secretion trait score and atrophy score,OSDI scores of observation group at 1 week and 4 weeks after the operation were all significantly lower than those of control group,the SQOL-DVI scores were significantly significantly higher than those of control group,the differences were statistically significant(P<0.05).Conclusion:The clinical effect of preoperative pulsed light combined with meibomian gland massage in the treatment of patients with cataract complicated with MGD is better,and it is helpful to the control of adverse effects of cataract surgery for ocular state of patients and it has active improvement for related life quality.

关 键 词：白内障 脉冲光 睑板腺按摩 睑板腺功能障碍 

分 类 号：R779.6[医药卫生—眼科]