Malignant vasovagal syncope in children  

作　　者：Wen-Rui Xu Hong-Fang Jin Jun-Bao Du Ying Liao 

机构地区：[1]Department of Pediatrics,Children’s Medical Center,Peking University First Hospital,No.8,Xishiku Street,West District,Beijing,100034,China [2]State Key Laboratory of Vascular Homeostasis and Remodeling,Peking University,Beijing,100191,China

出　　处：《World Journal of Pediatrics》2025年第1期41-47,共7页世界儿科杂志(英文版)

基　　金：National High-Level Hospital Clinical Research Funding(Multi-center Clinical Research Project of Peking University First Hospital)(2022CR59);Clinical Medicine Plus X—Young Scholars Project(PKU2022LCXQ028);the Fundamental Research Funds for the Central Universities,China.

摘　　要：Background Malignant vasovagal syncope(VVS)is a unique form of cardioinhibitory VVS,characterized by prolonged asystole.To deepen the understanding of this distinct type of VVS in children,this article reviews advancements in the potential pathogenesis,diagnostic approaches,clinical significance,and treatment controversies of malignant VVS in pediatric patients.Data sources This article was developed by reviewing the literature and studies in databases including PubMed and Chinese Journal Full-text Database up to September 2024.Search terms included“malignant vasovagal syncope”AND“children”or“vasovagal syncope”AND“asystole”AND“children”.Results To date,studies focused on malignant VVS in children remain limited.Theoretically,children with malignant VVS are at risk of physical or mental impairment due to this cardiac asystole,though no definite conclusions have been reached.The mechanism underlying the significant cardiac inhibition in malignant VVS remains unclear,and the treatment strategy of malignant VVS is debatable.Conclusions The understanding of children with malignant VVS is insufficient.Further research is required to evaluate the clinical features and the pathogenesis of pediatric VVS with cardiac asystole and to establish effective management strategies for malignant VVS.

关 键 词：ASYSTOLE DIAGNOSIS PATHOGENESIS PEDIATRICS Treatment Vasovagal syncope 

分 类 号：R725.4[医药卫生—儿科]