轻度缺血性结肠炎住院时间的影响因素分析  

Analysis of influencing factors on hospitalization time for mild ischemic colitis

作　　者：方丽莎 李欢[1] 龙辉[1] 吴清明[1] FANG Lisha;LI Huan;LONG Hui;WU Qingming(Department of Gastroenterology,Tianyou Hospital Affiliated to Wuhan University of Science and Technology,Wuhan 430064,China)

机构地区：[1]武汉科技大学附属天佑医院消化内科,武汉430064

出　　处：《医学新知》2025年第4期436-441,共6页New Medicine

基　　金：职业危害识别与控制湖北省重点实验室开放基金项目(OHIC2021G03)。

摘　　要：目的分析轻度缺血性结肠炎(ischemic colitis,IC)患者住院时间的影响因素。方法回顾性选取2017年1月至2024年7月于武汉科技大学附属天佑医院就诊住院的轻度IC患者为研究对象。根据住院时间分为≤7 d组和>7 d组,收集两组患者的一般情况、既往病史、入院时的临床表现、入院后初次实验室检查指标、结肠镜检查及影像学检查等资料。将单因素分析具有统计显著性的影响因素纳入多因素Logistic回归分析以确定影响患者住院时间的影响因素。结果共纳入132例轻度IC患者,其中住院时间≤7 d组60例,>7 d组72例。单因素分析显示两组患者在脑卒中、白细胞计数、中性粒细胞计数、血钠水平、腹部CT提示脂肪间隙模糊、肠系膜动脉CTA提示动脉粥样硬化及管腔狭窄方面的差异具有统计学意义(P<0.05)。多因素Logistic回归分析显示脑卒中史[OR=4.319,95%CI(1.108,16.837)]、低血钠水平[OR=0.843,95%CI(0.729,0.976)]、腹部CT提示脂肪间隙模糊[OR=4.392,95%CI(1.308,14.749)]、肠系膜动脉CTA提示动脉管腔狭窄[OR=3.882,95%CI(1.273,11.836)]是轻度IC患者住院时间>7 d的独立危险因素(P<0.05)。结论轻度IC患者住院时间受多种因素影响,其中脑卒中病史、入院后首次实验室检查血钠水平偏低、腹部CT提示脂肪间隙模糊和肠系膜动脉CTA提示动脉狭窄与住院时间>7 d密切相关。Objective To analyze the factors influencing hospitalization duration in patients with ischemic colitis(IC).Methods A retrospective study was conducted on patients with mild IC of Tianyou Hospital affiliated to Wuhan University of Science and Technology from January 2017 to July 2024.Patients were categorized into two groups based on hospitalization duration(≤7 days and>7 days).Data on general characteristics,medical history,clinical manifestations at admission,initial laboratory test results,colonoscopy findings,and imaging examinations were collected for both groups.Factors with statistical significance in univariate analysis were included in multivariate Logistic regression analysis to identify risk factors influencing hospitalization duration.Results A total of 132 patients with mild IC were included in the study,with 60 patients in the≤7days group and 72 patients in the>7 days group.Univariate analysis showed statistically significant differences between the two groups in stroke,white blood cell count,neutrophils count,blood sodium level,blurred fat space on abdominal CT,and mesenteric artery stenosis detected by CTA(P<0.05).Multivariate Logistic regression analysis identified a history of stroke[OR=4.319,95%CI(1.108,16.837)],hyponatremia[OR=0.843,95%CI(0.729,0.976)],blurred fat space on abdominal CT[OR=4.392,95%CI(1.308,14.749)],and mesenteric artery stenosis detected by CTA[OR=3.882,95%CI(1.273,11.836)]as independent risk factors for hospitalization duration>7 days(P<0.05).Conclusion The hospitalization duration of patients with mild IC is influenced by multiple factors.A history of stroke,hyponatremia on initial laboratory tests,blurred fat space on abdominal CT,and mesenteric artery stenosis detected by CTA are closely associated with a hospitalization duration of more than 7 days.

关 键 词：缺血性结肠炎 住院时间 影响因素 

分 类 号：R574[医药卫生—消化系统]