长骨釉质瘤合并骨巨细胞瘤1例并文献复习  

Adamantinoma of long bones combined with giant cell tumor of bone:a case report and literature review

作　　者：朱雅丽 范梦 吴娟[1,3] 杨桂芳 ZHU Yali;FAN Meng;WU Juan;YANG Guifang(Department of Pathology,Zhongnan Hospital of Wuhan University,Wuhan 430071,China;Department of Pathology,Wuxue Second People's Hospital,Huanggang 435400,Hubei Province,China;Department of Pathology,Zaoyang First People's Hospital,Xiangyang 441200,Hubei Province,China)

机构地区：[1]武汉大学中南医院病理科,武汉430071 [2]武穴市第二人民医院病理科,湖北黄冈435400 [3]枣阳市第一人民医院病理科,湖北襄阳441200

出　　处：《医学新知》2025年第4期476-482,共7页New Medicine

基　　金：湖北省卫生和计划生育委员会联合基金项目(WJ2018H0018)。

摘　　要：长骨釉质瘤和骨巨细胞瘤常为孤立病变,这两种肿瘤并发于一位患者极其罕见。本文报道一例17岁女性患者,因右膝疼痛入院,影像提示右股骨下端及右胫骨上端骨质破坏伴软组织影,临床医生考虑骨肿瘤并行肿瘤刮除术,术后病理诊断右股骨病灶为骨巨细胞瘤、右胫骨病灶为长骨釉质瘤,术后恢复良好,随访至今无复发及转移。本文复习相关文献,总结骨巨细胞瘤及长骨釉质瘤临床表现、影像学特点、病理形态特征及治疗方式。Adamantinoma of long bone(AD)and giant cell tumor of bone(GCTB)typically present as solitary bone lesions.It is extremely rare for both types of tumors to occur simultaneously in one patient.This article reports a 17-year-old female patient who was admitted to the hospital due to right knee pain.Imagery suggested that the lower of the right femur and the upper of the right tibia had undergone bone destruction with the formation of soft tissue shadows.The clinicians diagnosed bone tumors and perform tumor curettage.The postoperative pathological diagnosis of the right femur lesion was GCTB,and the right tibia lesion was AD.The postoperative recovery was favorable,and no recurrence or metastasis so far.In this paper,we review the relevant literatures and summarize the clinical manifestations,imaging characteristics,pathomorphological features,and treatment modalities of GCTB and AD.

关 键 词：长骨釉质瘤 骨巨细胞瘤 病理诊断 骨肿瘤 

分 类 号：R738.1[医药卫生—肿瘤]