胃癌病人大网膜转移率的初步探索(Dragon 05临床预试验)  

Preliminary exploration of greater omentum metastasis rate in patients with gastric cancer:clinical pilot study of Dragon 05 trial

作　　者：华子辰 梅郁 李琛[1] 严超[1] 燕敏[1] 朱正纲[1] 姚学新[1] HUA Zichen;MEI Yu;LI Chen;YAN Chao;YAN Min;ZHU Zhenggang;YAO Xuexin(Department of General Surgery,Shanghai Institute of Digestive Surgery,Shanghai Key Laboratory of Gastric Neoplasms,Ruijin Hospital,Shanghai Jiaotong University School of Medicine,Shanghai 200025,China)

机构地区：[1]上海交通大学医学院附属瑞金医院普外科、上海消化外科研究所、上海市胃肿瘤重点实验室,上海200025

出　　处：《外科理论与实践》2025年第1期41-46,共6页Journal of Surgery Concepts & Practice

摘　　要：目的:本研究拟探究胃癌大网膜转移率。方法:收集2020年5月于上海瑞金医院接受胃癌根治术的病人信息,分析病人的临床病理特征及大网膜转移的危险因素,分析病人的复发及生存情况。结果:本研究共纳入59例胃癌病人。2例(3.4%)存在大网膜转移。1例术后病理分期为pT4aN3bM0,另1例新辅助治疗后术后病理分期为ypT4bN1M0。纳入研究的病人3年总生存率为87.9%。结论:胃癌大网膜转移率较低,且大网膜转移的病理分期偏晚。为进一步验证该临床问题,应开展联合大网膜切除与保留大网膜的胃癌根治术两组之间的临床前瞻性随机对照研究。Objective To investigate the rate of greater omentum metastasis in gastric cancer(GC).Methods General informations of patients with GC who underwent radical gastrectomy at Shanghai Ruijin Hospital in May 2020 were collected,and their clinicopathological characteristics were analyzed to find risk factors of greater omentum metastasis.Recurrence and survival were also assessed.Results A total of 59 patients with GC were included in the study,of which 2(3.4%)had greater omentum metastasis.One patient presented a pathological stage of pT4aN3bM0 and another ypT4bN1M0.The 3-year overall survival rate of patients in the study was 87.9%.Conclusions The rate of greater omentum metastasis was relatively low,and patients with greater omentum metastasis had an more advanced pathological stage.To further validate this clinical issue,a prospective randomized controlled clinical study should be conducted between radical gastrectomy with omentectomy and omentum-preserving radical gastrectomy.

关 键 词：胃癌 大网膜 手术 

分 类 号：R735.2[医药卫生—肿瘤]