功能磁共振成像在儿童Tourette综合征中的应用进展  

Application progress of functional magnetic resonance imaging in children with Tourette's syndrome

作　　者：陆彦婷 刘秀梅 LU Yanting;LIU Xiumei(Department of Child Healthcare,College of Clinical Medicine for Obstetrics&Gynecology and Pediatrics,Fujian Medical Univer-sity,Fujian Children's Hospital(Fujian Branch of Shanghai Children's Medical Center),Fuzhou 350012,China)

机构地区：[1]福建医科大学妇儿临床医学院、福建省儿童医院(上海儿童医学中心福建医院)儿童保健科,福建福州350012

出　　处：《医学影像学杂志》2025年第3期108-111,共4页Journal of Medical Imaging

基　　金：国家自然科学基金项目(编号:81871076);福建省自然科学基金资助项目(编号:2021J01424);福建省儿童医院科技创新启动基金(高层次人才引进配套科研项目)资助计划(编号:YCXY202103)。

摘　　要：Tourette综合征(TS)是一种慢性神经发育障碍性疾病。发病机制尚不清楚。功能磁共振成像(fMRI)作为一种无创的影像学技术,在研究大脑的自发脑电活动和脑部的功能连接方面存在优势,在儿童TS诊断、鉴别诊断、发病机制研究方面有较好的应用前景。本综述总结了近年来fMRI在探索TS儿童大脑区域和功能网络方面的应用,旨在阐明fMRI为儿童TS提供神经影像学生物学标志物的潜在价值。Tourette syndrome(TS)is a chronic neurodevelopmental disorder.The exact mechanism of its onset remains un-clear.Functional magnetic resonance imaging(fMRI),as a noninvasive imaging technique,offers advantages in studying sponta-neous brain electrical activity and functional connectivity in the brain.It has promising applications in diagnosing and distinguish-ing TS in children,as well as in studying the mechanisms of its onset.This review summarizes the recent applications of fMRI in exploring brain regions and functional networks in children with TS,aiming to elucidate the potential value of functional MRI as a neuroimaging biomarker for children with TS.

关 键 词：功能磁共振成像 TOURETTE综合征 儿童 功能连接 

分 类 号：R742[医药卫生—神经病学与精神病学] R445.2[医药卫生—临床医学]