急性缺血性脑卒中后并发脑卒中-心脏综合征的危险因素研究  

Study on the risk factors for stroke-heart syndrome following acute ischemic stroke

作　　者：姚建珍[1] 汪勇军[1] 吴安[1] 曹爱琴[1] YAO Jianzhen;WANG Yongjun;WU An;CAO Aiqin(Department of Neurosurgery,Quzhou People's Hospital,Quzhou 324000,China)

机构地区：[1]衢州市人民医院神经外科,324000

出　　处：《心电与循环》2025年第2期181-184,共4页Journal of Electrocardiology and Circulation

摘　　要：目的探讨急性缺血性脑卒中(AIS)并发脑卒中-心脏综合征(SHS)的危险因素。方法回顾性选择2022年5月至2023年11月衢州市人民医院收治的143例AIS患者,根据是否发生SHS,将患者分为观察组57例及对照组86例,比较两组患者的一般资料,采用多因素logistic回归分析AIS并发SHS的危险因素,采用ROC曲线分析各指标预测AIS并发SHS的效能。结果观察组年龄、美国国立卫生研究院卒中量表评分、最大病灶直径、慢性阻塞性肺疾病(COPD)占比、中性粒细胞计数、脑钠肽、乳酸脱氢酶、血肌酐水平高于对照组,差异均有统计学意义(均P<0.05)。多因素logistic回归分析显示,年龄、最大病灶直径、COPD、中性粒细胞计数、脑钠肽、乳酸脱氢酶是AIS并发SHS的危险因素(均P<0.05)。6项指标联合预测AIS并发SHS的AUC高于其他单一指标预测(均P<0.05)。结论AIS后发生SHS的相关危险因素有年龄、最大病灶直径、COPD、中性粒细胞计数、脑钠肽、乳酸脱氢酶。Objective To analyze the risk factors for stroke-heart syndrome(SHS)following acute ischemic stroke(AIS).Methods A total of 143 AIS patients admitted to Quzhou People's Hospital from May 2022 to November 2023 were retrospectively selected.According to whether SHS occurred,the patients were divided into observation group(57 cases)and control group(86 cases).The clinical data of the two groups were compared.Multivariate logistic regression was used to analyze the risk factors for SHS following AIS.ROC curve was used to determine the predictive efficacy of related risk factors for SHS.Results The age,National Institutes of Health Stroke Scale score,stroke lesion size,proportion of chronic obstruct pulmonary disease(COPD),neutrophil count,brain natriuretic peptide,lactate dehydrogenase,and serum creatinine levels in observation group were significantly higher than those in control group(all P<0.05).Multivariate logistic regression analysis showed that age,stroke lesion size,COPD,neutrophil count,brain natriuretic peptide and lactate dehydrogenase were the risk factors for SHS(all P<0.05).The AUC of a combination of above 6 parameters for predicting SHS was significantly higher than that of any single parameter(all P<0.05).Conclusion The related risk factors for SHS after AIS include age,lesion size,COPD,neutrophil count,brain natriuretic peptide and lactate dehydrogenase.

关 键 词：急性缺血性脑卒中 脑卒中-心脏综合征 危险因素 预测 

分 类 号：R743.3[医药卫生—神经病学与精神病学]