卒中心脏综合征的流行病学、发生机制、诊断及防治方法  

Epidemiology,Pathogenesis,Diagnosis,Prevention and Treatment Method of Stroke-Heart Syndrome

作　　者：陈宗敏 李梦萍 顾轶涛 殷梅[1] CHEN Zongmin;LI Mengping;GU Yitao;YIN Mei(Department of Neurology,the Second Affiliated Hospital of Kunming Medical University,Kunming 650000,China)

机构地区：[1]昆明医科大学第二附属医院神经内科,云南省昆明市650000

出　　处：《实用心脑肺血管病杂志》2025年第6期1-5,共5页Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease

基　　金：云南省科技厅科技计划课题(202203AC100007-2)。

摘　　要：卒中与心肌损伤互为因果,目前心脑同治是全球研究热点。卒中心脏综合征为急性脑梗死后最常见的并发症之一,其不仅会增加患者预后不良及入住重症监护病房甚至死亡的风险,还会导致患者发病后5年内卒中复发率及心血管不良预后发生率明显升高。本文简述了卒中心脏综合征的流行病学,全面介绍了其四大发生机制,包括自主神经失衡、下丘脑-垂体-肾上腺(HPA)轴被激活、免疫炎症和炎症反应及肠道菌群失调,还归纳了其诊断及防治方法,以期为卒中心脏综合征的进一步研究及临床防治提供参考。Stroke and myocardial injury are mutually causal,and currently the treatment of the heart and brain is a global research hotspot.Stroke cardiac syndrome is one of the most common complications after acute cerebral infarction.It not only increases the risk of poor prognosis and admission to intensive care units,but also leads to a significant increase in stroke recurrence rate and cardiovascular poor prognosis within 5 years after onset.This article briefly describes the epidemiology of stroke-heart syndrome,comprehensively introduces its four major pathogenesis,including autonomic nervous imbalance,hypothalamic-pituitary-adrenal(HPA)axis activation,immune inflammation and inflammatory reaction,and intestinal flora imbalance,and summarizes its diagnosis and prevention methods,in order to provide reference for further research and clinical prevention and treatment of stroke heart syndrome.

关 键 词：卒中 卒中心脏综合征 流行病学 发病机制 诊断 治疗 综述 

分 类 号：R743[医药卫生—神经病学与精神病学]