翼状胬肉切除联合自体角膜缘干细胞移植手术对患者眼表功能和视力水平的影响研究  

Effect of Pterygium Excision Combined with Autologous Limbal Stem Cell Transplantation on Ocular Surface Function and Visual Acuity of Patients

作　　者：钟守明 ZHONG Shouming(Department of Otorhinolaryngology,Suichuan County Hospital of Traditional Chinese Medicine,Suichuan 343900,Jiangxi,China)

机构地区：[1]遂川县中医院五官科,江西遂川343900

出　　处：《医学信息》2025年第8期110-113,共4页Journal of Medical Information

摘　　要：目的 分析翼状胬肉切除联合自体角膜缘干细胞移植手术(ALSCT)的临床应用价值。方法 选取2021年7月1日-2022年12月31日遂川县中医院收治的80例翼状胬肉患者,经随机抽签法分为对照组(40例)与观察组(40例),对照组行翼状胬肉切除手术治疗,观察组在其基础上联合ALSCT治疗,比较两组眼表功能恢复时间(角膜上皮修复时间、创面愈合时间)、视力水平[裸眼视力(UCVA)、角膜散光度(CAD)]、术后并发症、胬肉复发率(术后6个月)。结果 观察组角膜上皮修复时间、创面愈合时间短于对照组(P<0.05);术后1个月,两组UCVA高于术前,CAD低于术前,且观察组UCVA高于对照组,CAD低于对照组(P<0.05);观察组术后并发症发生率及胬肉复发率均低于对照组(P<0.05)。结论 翼状胬肉切除联合ALSCT可缩短患者的术后眼表功能恢复时间,提升视力水平,且术后并发症少、胬肉复发风险低。Objective To analyze the clinical application value of pterygium excision combined with autologous limbal stem cell transplantation(ALSCT).Methods A total of 80 patients with pterygium admitted to Suichuan County Hospital of Traditional Chinese Medicine from July 1,2021 to December 31,2022 were selected and randomly divided into control group(40 patients) and observation group(40 patients).The control group was treated with pterygium excision,and the observation group was treated with ALSCT on the basis of the control group.The recovery time of ocular surface function(corneal epithelial repair time,wound healing time),visual acuity level [uncorrected visual acuity(UCVA),corneal astigmatism(CAD)],postoperative complications and pterygium recurrence rate(6 months after operation) were compared between the two groups.Results The corneal epithelial repair time and wound healing time in the observation group were shorter than those in the control group( P<0.05).One month after operation,UCVA in the two groups was higher than that before operation,CAD was lower than that before operation,UCVA in the observation group was higher than that in the control group,and CAD was lower than that in the control group( P<0.05).The incidence of postoperative complications and recurrence rate of pterygium in the observation group were lower than those in the control group( P <0.05).Conclusion Pterygium excision combined with ALSCT can shorten the recovery time of ocular surface function and improve the visual acuity,with fewer postoperative complications and lower risk of pterygium recurrence.

关 键 词：翼状胬肉 翼状胬肉切术 自体角膜缘干细胞移植手术 眼表功能 视力水平 

分 类 号：R779.6[医药卫生—眼科]