妊娠期子宫肌瘤大小变化分析  

Analysis of the uterine myoma size changes of pregnant women during pregnancy

作　　者：李文静[1] 李明明 蒲兰香 牟雪剑 苏士利 LI Wenjing;LI Mingming;PU Lanxiang;MU Xuejian;SU Shili(Shandong Provincial Maternal and Child Health Care Hospital Affiliated to Qingdao University,Key Laboratory of Birth Regulation and Control Technology of National Health Commission of China,Jinan,250014)

机构地区：[1]青岛大学附属山东省妇幼保健院,国家卫生健康委生育调控技术重点实验室,济南250014

出　　处：《中国计划生育学杂志》2025年第4期951-955,共5页Chinese Journal of Family Planning

摘　　要：目的:探讨妊娠期子宫肌瘤的变化趋势。方法:选取2016年7月-2021年6月本院247例合并子宫肌瘤的孕产妇为研究对象。根据妊娠11~13^(+6)周时超声报告最大肌瘤的平均径线分为<3cm组129例,3~5cm组80例,≥5cm组38例,比较3组肌瘤变化情况。并对104例子宫肌瘤呈线性增长的临床资料进行分析。结果:<3cm组、3~5cm组、≥5cm组中肌瘤线性增长者分别占50.4%、38.8%和21.1%,肌瘤平均径线越小,线性增长的几率越高(P<0.05)。孕期<3cm肌瘤增长趋势最显著(P<0.05),3~5cm肌瘤与直径≥5cm肌瘤增长趋势无统计学差异(P>0.05)。妊娠期子宫肌瘤有缩小趋势,11~13^(+6)孕周平均径线大者缩小几率上升,≥5cm肌瘤有50%缩小(P<0.05)。妊娠期呈线性增长的子宫肌瘤占42.1%,在妊娠22~26周后肌瘤增长趋势明显上升(P<0.05)。结论:妊娠期子宫肌瘤多呈非线性变化,变化趋势与妊娠11~13^(+6)周时肌瘤平均径线有关,<3cm肌瘤线性增长几率最高,增长趋势最显著,≥5cm肌瘤缩小几率显著升高。线性增长肌瘤在妊娠22~26周后增长趋势明显上升。Objective:To explore the trend of the uterine myoma size changes of pregnant women during pregnancy.Methods:A total of 247 pregnant women with uterine myoma in the hospital from July 2016 to June 2021 were selected as the research objects.According to the average diameter of the largest uterine myoma of the women reported by ultrasound during 11-13^(+6)gestational weeks,these women were divided into three groups,including group A(129 women with the uterine myomas average size<3cm),group B(80 women with the uterine myomas average size of 3-5 cm)and group C(38 women with the uterine myomas average size≥5cm).The changes of the uterine myomas of the women were compared among the three groups.The clinical data of 104 women with the linear growth of uterine myomas were analyzed.Results:The linear growth rate of the uterine myomas of the women in group A,in group B and in group C were 50.4%,38.8%and 21.1%,respectively.The probability of the uterine myomas with the linear growth of women with less average diameter of uterine myomas was higher(P<0.05).The growth trend of the uterine myomas of the women in group A was obvious significantly(P<0.05),and there was no significant difference in the growth trend of the uterine myomas of the women between group B and group C(P>0.05).There was a tendency for the uterine myomas to shrink of the women during pregnancy,and the probability of the uterine myomas shrinking of the women increased with the increase of the average diameter of their uterine myomas during 11-13^(+6)gestational weeks,and the rate of the uterine myomas shrinking of the women with≥5cm uterine myomas was 50%(P<0.05).The proportion of the uterine myomas increased linearly of the women during pregnancy was 42.1%,and the growth trend of the uterine myomas of the women increased significantly after 22-26 gestational weeks(P<0.05).Conclusion:The uterine myomas of the pregnant women presents the nonlinear change during pregnancy,and the change trend of which was related to the average diameter of their uterine myo

关 键 词：妊娠 子宫肌瘤 变化趋势 肌瘤大小 

分 类 号：R737.33[医药卫生—肿瘤]