脂肪肉瘤免疫学特征的研究进展  

Research progress on the immunological characteristics of liposarcoma

作　　者：何晓霞 赵欢欢 HE Xiaoxia;ZHAO Huanhuan(Department of Digestive Medicine,Baoding No.1 Central Hospital,Baoding 071000,Hebei Province,China;Department of Orthopedics,Baoding No.1 Central Hospital,Baoding 071000,Hebei Province,China)

机构地区：[1]保定市第一中心医院消化内科,河北保定071000 [2]保定市第一中心医院骨科,河北保定071000

出　　处：《数理医药学杂志》2025年第4期297-302,共6页Journal of Mathematical Medicine

摘　　要：脂肪肉瘤是一种源于间充质组织的恶性软组织肿瘤,治疗手段目前以手术切除为主,而对于已出现远处转移的患者可辅助进行蒽环类细胞毒性药物的全身性治疗。由于肿瘤的异质性,脂肪肉瘤免疫疗法的研究进展较为缓慢。本文聚焦脂肪肉瘤复杂的免疫学特征,对其免疫疗法的研究进展进行综述,旨在为脂肪肉瘤免疫疗法的优化提供一定参考。Liposarcoma is a malignant soft tissue tumor originating from mesenchymal tissue.Currently,surgical resection is the main treatment method for liposarcoma,and systemic therapy with anthracycline cytotoxic drugs can be used for the patients with distant metastasis.Due to the heterogeneity of the tumor,the progress of immunotherapy for liposarcoma is blocked.This paper will focus on the complex immunological characteristics of liposarcoma,and review the progress of its immunotherapy,aiming to provide a few references for the optimization of immunotherapy for liposarcoma.

关 键 词：脂肪肉瘤 肿瘤浸润淋巴细胞 免疫检查点 免疫疗法 

分 类 号：R730.3[医药卫生—肿瘤]