中国中老年慢性肺病患者抑郁症发生率及影响因素分析  

Prevalence and Influencing Factors of Depression in Chinese Middle-Aged and Elderly Patients with Chronic Pulmonary Diseases

作　　者：徐紫洁 王兆慧 刘志婷 龙博 李轩毅 丁爽 XU ZiJie;WANG ZhaoHui;LIU ZhiTing;LONG Bo;LI XuanYi;DING Shuang(Xuzhou Medical University,The Affiliated Hospital of Xuzhou Medical University,Xuzhou,Jiangsu 221000,China;Department of Otorhinolaryngology,The Affiliated Hospital of Xuzhou Medical University,The Affiliated Hospital of Xuzhou Medical University,Xuzhou,Jiangsu 221000,China;Department of Clinical Laboratory Examination,The Affiliated Hospital of Xuzhou Medical University,Xuzhou,Jiangsu 221000,China)

机构地区：[1]徐州医科大学,江苏徐州221000 [2]徐州医科大学附属医院耳鼻咽喉科,江苏徐州221000 [3]徐州医科大学附属医院检验科,江苏徐州221000

出　　处：《临床肺科杂志》2025年第5期681-687,共7页Journal of Clinical Pulmonary Medicine

基　　金：江苏省中医药科技发展计划项目课题(QN202009)。

摘　　要：目的研究中国中老年慢性肺病患者抑郁症的发病率及其影响因素,为改善中老年慢性肺部疾病患者的心理健康状况,制定预防、控制和干预策略提供理论依据。方法本研究的样本来自2018年中国健康与养老追踪调查(China Health and Retirement Longitudinal Study,CHARLS)的调查数据,选取年龄≥45岁的中老年慢性肺病患者作为研究对象,采用二元Logistic回归分析抑郁症的影响因素,应用R软件建立并验证中国中老年慢性肺病人群抑郁的列线图模型。结果本研究共纳入858例慢性肺病的中老年人,抑郁症发生率为56.4%(484/858)。二元Logistic回归筛选出性别(OR:0.653;95%CI:0.450~0.947,P=0.025)、居住地(OR:1.540;95%CI:1.040~2.290,P=0.031)、吸烟(OR:0.578;95%CI:0.356~0.928,P=0.024)、自评健康状况(OR:0.437;95%CI:0.250~0.755,P=0.004)、听力障碍(OR:2.330;95%CI:1.300~4.280,P=0.005)、生活满意度(OR:0.262;95%CI:0.150~0.450,P<0.001)、儿童满意度(OR:0.298;95%CI:0.130~0.630,P=0.003)是中国中老年慢性肺病患者发生抑郁症的影响因素,并据此建立列线图,该模型的平均校准曲线的绝对误差均值为0.009,ROC曲线下面积0.785(95%CI:0.775~0.751)。结论女性、居住在农村、不吸烟、自评健康状况欠佳、听力障碍、生活满意度低、儿童时期生活满意度低是我国中老年慢性肺病患者发生抑郁的危险因素。中国中老年慢性肺病抑郁症发生率的列线图模型具有较高的预测价值。Objective To investigate the prevalence of depression and its influencing factors among middle-aged and elderly patients with chronic pulmonary disease in China,and to provide a theoretical basis for improving the mental health status of middle-aged and elderly patients with chronic lung diseases and formulating prevention,control,and intervention strategies.Methods The sample of this Study comes from the survey data of the 2018 China Health and Retirement Longitudinal Study(CHARLS).Middle-aged and elderly patients aged≥45 years old with chronic lung disease were selected as the research objects.The influence factors of depression were analyzed by binary Logistic regression,and R software was used to establish and verify the column-line model of depression in Chinese middle-aged and elderly people with chronic lung disease.Results A total of 858 middle-aged and elderly patients with chronic lung disease were included in this study,and the incidence of depression was 56.4%(484/858).Binary Logistic regression screened gender(OR:0.653;95%CI:0.450-0.947,P=0.025),residence(OR:1.540;95%CI:1.040-2.290,P=0.031),smoking(OR:0.578;95%CI:0.356-0.928,P=0.024),self-rated overall health status(OR:0.437;95%CI:0.250-0.755,P<0.001),hearing impairment(OR:2.330;95%CI:1.300-4.280,P=0.005),life satisfaction(OR:0.262;95%CI:0.150-0.450,P<0.001),children′s satisfaction(OR:0.298;95%CI:0.130-0.630,P=0.003)were influencing factors for depression in middle-aged and elderly patients with chronic lung disease in China,and a column graph was established accordingly.The mean absolute error of the mean calibration curve of this model was 0.009,and the area under the ROC curve was 0.785(95%CI:0.775-0.751).Conclusion Female,living in rural areas,non-smoking,poor self-rated general health status,hearing impairment,low life satisfaction and low childhood satisfaction are risk factors for depression in middle-aged and elderly patients with chronic lung disease in China.The column-graph model of the incidence of chronic pulmonary depression in midd

关 键 词：中老年人 慢性肺病 抑郁症 影响因素 中国健康与养老追踪调查 

分 类 号：R749.4[医药卫生—神经病学与精神病学]