包皮疣状黄瘤临床病理学分析及文献复习  

Verruciform xanthoma on prepuce a clinicopathological analysis and literature review

作　　者：纪海勇 李亚玮 周福安 JI Haiyong;LI Yawei;ZHOU Fuan(Department of Urology and Pediatric Surgery,Ningjin People's Hospital,Dezhou,Shandong,253400,China;Department of Pathology,Ningjin People's Hospital,Dezhou,Shandong,253400,China)

机构地区：[1]宁津县人民医院泌尿、小儿外科,山东德州253400 [2]宁津县人民医院病理科,山东德州253400

出　　处：《当代医学》2025年第1期139-142,共4页Contemporary Medicine

摘　　要：疣状黄瘤(verruciform xanthoma,VX)是一种罕见的、良性皮肤黏膜病变,临床表现无特异性,不易诊断,需与多种良性、潜在恶性、恶性肿瘤相鉴别。本文报道1例包皮VX患者,探讨其临床特征、病理学形态、鉴别诊断及治疗方法。患者阴茎系带处包皮内板见一灰红疣状隆起,体积1.1 cm×0.7 cm×0.6 cm,表面粗糙,界限清楚,质韧。病理活检示上皮增生伴有明显角化不全,角化不全物内见中性粒细胞浸润,上皮嵴均匀拉长,真皮乳头内见大量黄瘤细胞聚集,并可见中性粒细胞、淋巴细胞、巨噬细胞和少量浆细胞弥漫性浸润。术后随访13个月,未见肿瘤复发。Verruciform xanthoma(VX)is a rare benign lesion of the skin and mucosa,the clinical manifestation is not specific and the not easy to di agnose,it needs to be differentiated from a variety of benign,potentially malignant and malignant tumors.This paper reported 1 case of VX,and to analyze the clinical and pathological features,pathological morphology,differential diagnosis and treatment.There was a verrucous gray bulge in the inner prepuce of the patient's penis,with a volume of 1.1 cm×0.7 cm×0.6 cm,rough surface,clear boundary and tough texture.Pathological examination showed epithelial hyperplasia with marked keratosis,infiltration of neutrophil in keratosis,elongation of epithelial ridge,and accumulation of xanthoma cells in dermal papillae,diffuse infiltrates of neutrophil,lymphocyte,macrophages and a few plasma cells were seen.Follow up for 13 months after surgery showed no tumor recurrence.

关 键 词：包皮 疣状黄瘤 病理学 

分 类 号：R739.5[医药卫生—肿瘤]