4项传染性血清标志物在1826例精神病患者中的结果分析  

Analysis of 4 infectious serum markers in 1826 patients with psychosis

作　　者：蒋玉凤 李启凤 冯恒雨 邓倩 JIANG Yu-feng;LIQi-feng;FENG Heng-yu(Department of Clinical Laboratory,Yunnan Provincial Psychiatric Hospital/Mental Health Center Afiliated to Kunming Medical University,Yunnan Kunming 650224)

机构地区：[1]云南省精神病医院/昆明医科大学附属精神卫生中心医学检验科,云南昆明650224

出　　处：《医学检验与临床》2025年第3期7-10,共4页Medical Laboratory Science and Clinics

基　　金：昆明市卫生科技人才培养项目,项目编号:2018-SW(技)-02。

摘　　要：目的:对精神病医院住院患者乙肝表面抗原(HBsAg)、丙型肝炎病毒抗体(抗-HCV)、梅毒螺旋体抗体(抗-TP)、人类免疫缺陷病毒抗体(抗-HIV1/2)的检测结果分析,为预防医院感染,减少职业暴露提供依据。方法:对某精神病医院2021年4月-2021年12月间1826例住院患者进行抗-HIV1/2、HBsAg、抗-HCV、抗-TP检测,对比四项检测结果在临床科室、性别及年龄之间的差异。结果:1826例患者中HBsAg阳性52例,阳性率2.79%,抗-HCV阳性7例,阳性率0.3833%,抗-HIV1/2初筛阳性4例,阳性率0.219%,抗-TP/RPR阳性8例,阳性率0.43%,总阳性率差异具有统计学意义(P<0.05);四项传染病在不同科室分布情况主要集中在老年科,康复科和临床心理科;男女四项传染病检测总阳性率分别为4.8%和3.22%,差异有统计学意义(P<0.05),在不同年龄阶段总阳性率分别小于15岁0.78%,16~30岁2.14%,31~45岁6.17%,46~60岁6.32%,大于60岁后4.4%,差异具有统计学意义(P<0.05)。结论:对入院的精神病患者检测各项传染病血清指标,可指导医务人员对病人进行针对性治疗和防范,对预防病人交叉感染和减少医务人员职业暴露有重要意义。Objective:To analyze the detection results of hepatitis B surface antigen(HBsAg),hepatitis C virus antibody(anti-HCV),treponema pallidum antibody(anti-TP)and human immunodeficiency virus antibody(anti-HIV1/2)in patients hospitalized in psychiatric hospital,so as to provide evidence for preventing nosocomial infection and reducing occupational exposure.Methods:1826 hospitalized patients in a psychiatric hospital from April 2021 to December 2021 were tested for anti-HIV1/2,HBsAg,anti-HCV and anti-TP,and the four test results were compared between clinical departments,gender and age.Results:Among the 1826 patients,52 were HBsAg positive,with a positive rate of2.79%;7 were anti-HCV positive,with a positive rate of 0.3833%;4 were anti-HIV1/2 preliminary screening positive,with a positive rate of 0.219%;8 were anti-TP/RPR positive,with a positive rate of 0.43%;The total positive rate was statistically significant(P<0.05).The distribution of the four infectious diseases in different departments mainly concentrated in the geriatric department,rehabilitation department and clinical psychology department.The total positive rates of the four infectious disease tests were 4.8%and 3.22%in men and women,respectively,with statistical significance(P<0.05).The total positive rates in different age groups were 0.78%at under 15 years old,2.14%at 16-30 years old,6.17%at 31-45 years old,6.32%at 46-60 years old,and 4.4%at after more than 60 years old.The dfference was statistically significant(P<0.05).Conclusion:The detection ofserum indexes ofvarious infectious diseases in hospitalized psychiatric patients can guide medical staffto carry out targeted treatment and prevention of patients,and is of great significance for preventing cross-infection of patients and reducing occupational exposure of medical staff.

关 键 词：感染性标志物 精神病患者 职业暴露 梅毒 

分 类 号：R749[医药卫生—神经病学与精神病学]