喉镜内镜等离子消融术在早期声门型喉癌患者中的应用效果  

Application Effect of Laryngoscope Endoscopic Plasma Ablation in Early Glottic Laryngeal Carcinoma

作　　者：杨志远 张明 YANG Zhi-yuan;ZHANG Ming(Department of Otolaryngology,the Second People's Hospital of Jiaozuo City(the First Affliated Hospital of Henan Polytechnic University),Jiaozuo 454150,China)

机构地区：[1]河南理工大学第一附属医院(焦作市第二人民医院)耳鼻喉科,焦作454150

出　　处：《四川解剖学杂志》2024年第5期27-30,共4页Sichuan Journal of Anatomy

摘　　要：目的:探讨喉镜内镜等离子消融术在早期声门型喉癌中的应用效果.方法:选取2017 年5 月至2021 年1月本院收治的 106 例首次诊断为早期声门型喉癌患者作为研究对象.根据治疗方式,将其分为观察组(n=54,采用喉镜内镜等离子消融术治疗)和对照组(n=52,采用常规开放性手术).比较两组患者的手术情况、疼痛程度、并发症发生情况及复发率、嗓音功能.结果:观察组患者手术时间、住院时间均短于对照组,术中出血量少于对照组、呛咳评分低于对照组,术后视觉模拟评分(VAS)低于对照组,差异均有统计学意义(P<0.05).术后两组患者嗓音功能均有改善,且观察组标准化嗓声能量(NNE)、基频微扰(Jitter)及振幅微扰(Shimmer)各项指标均低于对照组,差异均有统计学意义(P<0.05).6 个月随访,两组患者复发率比较,差异无统计学意义(P>0.05),但观察组的并发症发生率(4/54,7.40%)低于对照组(20/52,38.46%),差异有统计学意义(P<0.05).结论:喉镜内镜等离子消融术在早期声门型喉癌中的应用效果好,与常规性开放手术比较,其手术时间短,患者术后恢复及嗓音功能恢复更好,临床应用价值更高.Objective:To explore the application effect of laryngoscope endoscopic plasma ablation in early glottic laryngeal carcinoma.Methods:A total of 106 cases of glottic laryngeal carcinoma of the first diagnosis admitted to our hospital from May 2017 to January 2021 were selected as the study subjects.They were divided into observation group(n=54,treated with laryngoscopy endoscopic plasma ablation)and control group(n=52,treated with conventional open surgery),according to the treatment method.The operation status,pain degree,complication occurrence,recurrence rate and voice function of the two groups were compared.Results:The operation time and hospitalization time of observation group were shorter than those of control group,the intraoperative bleeding was less than that of control group,the cough score was significantly lower than that of control group,and the postoperative visual analogue score(VAS)was lower than that of control group,the differences were statistically significant(P<0.05).After surgery,both groups improved their voice function,and normalized noise energy(NNE),fundamental frequency perturbation(Jitter)and amplitude perturbation(Shimmer)indicators of observation group were lower than those of control group,with statistically significant differences(P<0.05).After a 6-month follow-up,there was no statistically significant difference in the recurrence rate between the two groups of patients(P>0.05),but the incidence of complications in observation group(4/54,7.40%)was lower than that in control group(20/52,38.46%),and the difference was statistically significant(P<0.05).Conclusion:Laryngoscope endoscopic plasma ablation is effective in early glottic carcinoma.Compared with conventional open surgery,the operation time is shorter,the postoperative recovery and the recovery of voice function are better,and the clinical value is higher.

关 键 词：常规开放性手术 喉镜内镜等离子消融术 早期声门型喉癌 嗓音功能 

分 类 号：R739.65[医药卫生—肿瘤]