机构地区:[1]Third Hospital of Shanxi Medical University,Shanxi Bethune Hospital,Shanxi Academy of Medical Sciences,Tongji Shanxi Hospital,Taiyuan,030032,China [2]Department of Neurosurgery,First Hospital of Shanxi Medical University,Taiyuan,030001,China [3]Department of Neurosurgery,Shanxi Bethune Hospital,Shanxi Academy of Medical Sciences,Tongji Shanxi Hospital,Third Hospital of Shanxi Medical University,Taiyuan,030032,China [4]Department of Neurosurgery,The Second Affiliated Hospital of Nanchang University,Nanchang,330009,China
出 处:《Chinese Journal of Traumatology》2025年第2期118-123,共6页中华创伤杂志(英文版)
基 金:supported by Shanxi Provincial Department of Science and Technology[grant number 202203021221241].
摘 要:Purpose:Traumatic brain injury(TBI)is a significant public health issue that impacts individuals all over the world and is one of the main causes of mortality and morbidity.Decompressive craniectomy is the usual course of treatment.Basal cisternostomy has been shown to be highly effective as an alternative procedure to decompressive craniectomy.Methods:We conducted a retrospective cohort of patients who received surgery for severe TBI between January 2019 and March 2023.Inclusion criterias were patients between the ages of 18 and 70 years who met the diagnostic criteria for severe TBI at first presentation and who underwent surgical intervention.The exclusion criteria were patients who have severe multiple injuries at the time of admission;preoperative intracranial pressure>60 mmHg;cognitive impairment before the onset of the disease;hematologic disorders;or impaired functioning of the heart,liver,kidneys,or other visceral organs.Depending on the surgical approach,the patients were categorized into decompressive craniectomy group as well as basal cisternostomy group.General data and postoperative indicators,including Glasgow coma scale,intracranial pressure,etc.,were recorded for both groups of patients.Among them,the Glasgow outcome scale extended assessment at 6 months served as the primary outcome.After that,the data were statistically analyzed using SPSS software.Results:The trial enrolled 41 patients(32 men and 9 women)who met the inclusion criteria.Among them,25 patients received decompressive decompressive craniectomy,and 16 patients received basal cisternostomy.Three days postoperative intracranial pressure levels were 10.07±2.94 mmHg and 17.15±14.65 mmHg(p=0.013),respectively.The 6 months following discharge Glasgow outcome scale extended of patients was 4.73±2.28 and 3.14±2.15(p=0.027),respectively.Conclusion:Our study reveals that basal cisternostomy in patients with surgically treated severe TBI has demonstrated significant efficacy in reducing intracranial pressure as well as patient prognosis fo
关 键 词:Basal cisternostomy Cerebrospinal fluid Decompressive craniectomy Glymphatic system Intracranial pressure Traumatic brain injury CSF ICP TBI
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