蒙药防治肝纤维化信号通路调控机制研究进展  

Research Progress on the Regulatory Mechanism of Signal Pathways in the Prevention and Treatment of Hepatic Fibrosis by Mongolian Medicine

作　　者：阿地亚 边塔娜 巴图德力根[2] Adiya;Biantana;Batudeligen(Clinical Medical College,Inner Mongolia Minzu University,Tongliao,Inner Mongolia 028000;Affiliated Hospital of Inner Mongolia Minzu University,Tongliao,Inner Mongolia 028000)

机构地区：[1]内蒙古民族大学临床医学院,内蒙古通辽028000 [2]内蒙古民族大学附属医院,内蒙古通辽028000

出　　处：《中国民族医药杂志》2025年第3期42-45,共4页Journal of Medicine and Pharmacy of Chinese Minorities

基　　金：国家自然科学基金资助项目(2022YFC3502204)。

摘　　要：肝纤维化(Hepatic fibrosis,HF)是基于各种病因下形成的慢性肝病,其过程包括多种细胞因子的紊乱和氧化应激反应,通过多项复杂的信号通路引起此病。目前尚未对HF有根本治疗的药物,而民族医药通过其独特的理论体系和灵活的辨证施治在治疗HF方面有着明显的疗效,而其作用机制是通过多项信号通路实施的。现对HF的发病机制、常用蒙药复方及其抗HF作用机制信号通路实验研究方面进行总结,以期对后续学习和研究提供参考。Liver fibrosis is a chronic liver disease formed under various etiologies.Its process involves the disorder of multiple cytokines and oxidative stress responses,and this disease is caused through a number of complex signal pathways.Currently,there is no fundamental therapeutic drug for HF.However,ethnic medicine has obvious curative effects in treating HF through its unique theoretical system and flexible treatment based on syndrome differentiation,and its mechanism of action is implemented through a number of signal pathways.Now,a summary is made on the pathogenesis of HF,common Mongolian medicine compound prescriptions and the experimental research on the signal pathway of their anti-HF mechanism of action,in order to provide a reference for subsequent learning and research.

关 键 词：蒙药 信号通路 肝纤维化 

分 类 号：R570.5[医药卫生—消化系统]