低剂量联合超高分辨率CT在肺磨玻璃结节筛查中的应用  

Application of low-dose CT combined with ultra-high resolution CT in the screening of pulmonary ground glass nodules

作　　者：刘亚梅 Liu Yamei(Department of Radiology,Henan Provincial Staff Hospital,Zhengzhou 450000,China)

机构地区：[1]河南省职工医院放射科,郑州450000

出　　处：《临床医学》2025年第3期72-75,共4页Clinical Medicine

摘　　要：目的 探讨肺磨玻璃结节(GGN)筛查中应用低剂量CT(LDCT)联合超高分辨率CT(UHRCT)的价值。方法 选择河南省职工医院2022年1月至2024年1月收治的经手术病理证实的104例GGN患者为研究对象。所有患者均接受LDCT、UHRCT筛查诊断,将手术病理结果作为金标准,比较LDCT联合UHRCT诊断和二者单一诊断的结果及诊断效能;同时,以手术病理结果进行分组,分为良性结节组与恶性结节组,比较LDCT、UHRCT诊断的影像学特征。结果 104例GGN经手术病理证实病变结节110个,良性50例,恶性60例;LDCT检出良性59例,恶性51例;UHRCT检出良性58例,恶性52例;LDCT联合UHRCT诊断检出良性51例,恶性59例。LDCT联合UHRCT诊断在准确度与灵敏度上均高于二者单一诊断(P<0.05)。良性结节与恶性结节的LDCT影像学特征比较,毛刺、胸膜凹陷征、瘤肺界面、肿瘤微血管CT征、成分比较,差异未见统计学意义(P>0.05);但长径、短径、分叶、细支气管充血征比较,差异有统计学意义(P<0.05)。良性结节与恶性结节的UHRCT影像学特征比较,毛刺、细支气管充血征、胸膜凹陷征、瘤肺界面、肿瘤微血管CT征比较,差异未见统计学意义(P>0.05);但长径、短径、分叶、成分比较,差异有统计学意义(P<0.05)。结论 LDCT、UHRCT用于GGN筛查中均有一定的价值,根据各自的影像学特征能做出一定的鉴别诊断,但二者联合诊断可进一步提高筛查诊断价值,其诊断准确度与灵敏度更高,同时综合分析二者的影像学特征,能为临床诊治提供更多可靠的依据。Objective To investigate the value of low-dose CT(LDCT)combined with ultrahigh resolution CT(UHRCT)in the screening of pulmonary ground-glass nodule(GGN).Methods A total of 104 patients with GGN confirmed by surgery and pathology admitted to Henan Provincial Staff Hospital from January 2022 to January 2024 were selected as the study objects.All patients underwent LDCT and UHRCT screening and diagnosis,and the surgical pathological results were used as the gold standard to compare the results and diagnostic efficacy of LDCT combined with UHRCT and their single diagnosis.At the same time,the patients were divided into benign nodule group and malignant nodule group by surgical pathology,and the imaging characteristics of LDCT and UHRCT were compared.Results Among the 104 GCN cases,110 nodules were confirmed by operation and pathology,including 50 benign cases and 60 malignant cases.LDCT detected 59 benign cases and 51 malignant cases.UHRCT detected 58 benign cases and 52 malignant cases.LDCT combined with UHRCT detected 51 benign cases and 59 malignant cases.The accuracy and sensitivity of LDCT combined with UHRCT were higher than those of both single diagnosis(P<0.05).There was no significant difference in the LDCT imaging features of benign nodules and malignant nodules,including burr,pleural depression,tumor lung interface,CT signs of tumor microvessels and composition(P>0.05).However,there were significant differences in long diameter,short diameter,lobulation and bronchiole hyperemia(P<0.05).There was no significant difference in the UHRCT imaging features of benign nodules and malignant nodules,including burr,bronchiolar hyperemia,pleural depression,tumor-lung interface and tumor microvascular CT signs(P>0.05).However,the difference between long diameter,short diameter,foliation and composition was significant(P<0.05).Conclusions LDCT and UHRCT have certain value for GGN screening,and certain differential diagnosis can be made according to their respective imaging characteristics,but the combination of the two

关 键 词：肺磨玻璃结节 筛查诊断 低剂量CT 超高分辨率CT 影像学特征 良恶性结节 

分 类 号：R734.2[医药卫生—肿瘤]