银川地区农村妇女宫颈癌筛查结果分析  

Analysis of Cervical Cancer Screening Results of Rural Women in Yinchuan Area

作　　者：王敏 买莉 王佳陪 陈龙 王娟 WANG Min;MAI Li;WANG Jiapei;CHEN Long;WANG Juan(Department of Pathology,Yinchuan Maternal and Child Health Hospital,Yinchuan 750001,Ningxia,China)

机构地区：[1]银川市妇幼保健院病理科,宁夏银川750001

出　　处：《医学信息》2025年第7期100-104,共5页Journal of Medical Information

摘　　要：目的通过分析银川地区宫颈癌筛查结果,了解该地区宫颈癌的发病特点,为本地区宫颈癌防治提供策略。方法选取2021年1月-2022年1月银川地区农村妇女宫颈癌筛查25564例为观察对象,采用高危型人乳头瘤病毒(HR-HPV)基因检测作为初筛,HPV16型、18型阳性,其他型别HPV阳性且细胞学≥ASCUS转诊阴道镜检查及阴道镜下活组织病理检查。结果总体高危型HPV感染阳性率13.00%,其他12种高危型在低级别病变检出率中高于HPV16、18高危型,差异有统计学意义(P<0.05),高级别病变检出率高于其他12种高危型,但差异无统计学意义(P>0.05),宫颈癌检查率高于其他12种高危型,差异有统计学意义(P<0.05)。液基细胞学检查级别升高,病理阳性率随之升高(P<0.05)。低级别病变检出率为2.52%,高级别病变检出率为0.42%,宫颈癌检出率为0.012%。各县区低级别病变检出率及高级别病变检出率比较,差异均有统计学意义(P<0.05)。各县区低级别病变检出率比较,差异有统计学意义(P<0.05),各县区高级别病变检出率比较,差异有统计学意义(P<0.05)。结论在银川地区农村妇女宫颈癌筛查人群中,以HPV为初筛、TCT分流,宫颈癌前病变检出率较高。Objective To understand the characteristics of cervical cancer in Yinchuan by analyzing the results of cervical cancer screening,and to provide strategies for the prevention and treatment of cervical cancer in Yinchuan.Methods A total of 25564 rural women who underwent cervical cancer screening in Yinchuan area from January 2021 to January 2022 were selected as the observation objects.High-risk human papillomavirus(HR-HPV)gene detection was used as the primary screening to investigate HPV16 and 18 positive,and other types of HPV positive and cytology≥ASCUS referral colposcopy and colposcopy biopsy were analyzed.Results A total of 25564 people were screened in Yinchuan area,and the overall positive rate of high-risk HPV infection was 13.00%,and the detection rate of the other 12 high-risk types was higher than that of HPV16 and 18 high-risk types(P<0.05),the detection rate of high-grade lesions was higher than that of the other 12 high-risk types,but the difference was not statistically significant(P>0.05),and the detection rate of cervical cancer was higher than that of the other 12 high-risk types,and the difference was statistically significant(P<0.05).The level of liquid-based cytology increased,and the pathological positivity rate increased(P<0.05).The detection rate of low-grade lesions was 2.52%,that of high-grade lesions was 0.42%,and detection rate of cervical cancer was 0.012%.There was statistically significant difference in the detection rate of low-grade lesions and high-grade lesions among the counties(P<0.05).Conclusion Among the population of cervical cancer screening for rural women in Yinchuan area,the detection rate of cervical precancerous lesions is higher with HPV as the primary screening and TCT as the triage.

关 键 词：HPV感染 宫颈癌筛查 农村妇女 

分 类 号：R737.33[医药卫生—肿瘤]