超声辅助亚甲蓝示踪在早期乳腺癌前哨淋巴结活检中的应用价值  

Application value of ultrasound-assisted methylene blue tracing in sentinel lymph node biopsy of early breast cancer

作　　者：徐旺 金钟奎 罗才路 刘长山 罗小丹 刘学娟 XU Wang;JIN Zhongkui;LUO Cailu;LIU Changshan;LUO Xiaodan;LIU Xuejuan(Department of General Surgery Third Ward,Yichun People's Hospital,Jiangxi Province,Yichun 336000,China)

机构地区：[1]江西省宜春市人民医院普外科三病区,江西宜春336000

出　　处：《中国当代医药》2025年第9期59-62,共4页China Modern Medicine

基　　金：江西省卫生健康委科技计划项目(202410931)。

摘　　要：目的探讨早期乳腺癌患者前哨淋巴结活检术(SLNB)中采用超声辅助亚甲蓝示踪方法的临床价值。方法选取2023年5月至2024年5月宜春市人民医院收治的120例临床触诊阴性的早期乳腺癌患者作为研究对象,根据随机数字表法分为对照组及观察组,每组60例。对照组SLNB术前单纯注射亚甲蓝示踪法,观察组术前采取超声辅助亚甲蓝示踪法,比较两组前哨淋巴结(SLN)检出率,第1枚SLN检出时间与SLN操作时间,术后不良反应。结果观察组SLN检出率高于对照组,差异有统计学意义(P<0.05)。观察组SLN检出数多于对照组,差异有统计学意义(P<0.05)。观察组第1枚SLN检出时间、SLN操作时均短于对照组,差异有统计学意义(P<0.05)。观察组术后不良反应总发生率低于对照组,差异有统计学意义(P<0.05)。结论针对早期乳腺癌患者,在SLNB中采用超声辅助亚甲蓝示踪,能提高SLN检出率与检出数,缩短检出时间与SLN操作时间,且术后不良反应发生率低。Objective To investigate the clinical value of ultrasound-assisted methylene blue tracer in sentinel lymph node biopsy(SLNB)in patients with early breast cancer.Methods A total of 120 patients with early breast cancer with negative clinical palpation admitted to Yichun People's Hospital from May 2023 to May 2024 were selected as the study objects,and they were divided into control group and observation group according to random number table method,with 60 cases in each group.The control group was injected with methylene blue tracer before SLNB,and the observation group was treated with ultrasound-assisted methylene blue tracer before surgery.The detection rate of sentinel lymph node(SLN),the time of the first SLN detection and the operation time of SLN,and the postoperative adverse reactions were compared between the two groups.Results The detection rate of SLN in observation group was higher than that in control group,and the difference was statistically significant(P<0.05).The number of SLN detected in the observation group was higher than that in the control group,and the difference was statistically significant(P<0.05).The detection time and operation time of the first SLN in the observation group were shorter than those in the control group,and the differences were statistically significant(P<0.05).The total incidence of postoperative adverse reactions in observation group was lower than that in control group,and the difference was statistically significant(P<0.05).Conclusion For patients with early breast cancer,the use of ultra-sound-assisted methylene blue tracing in SLNB can improve the detection rate and number of SLN,shorten the detection time and SLN operation time,and the incidence of postoperative adverse reactions is low.

关 键 词：乳腺癌 超声 亚甲蓝 前哨淋巴结活检术 

分 类 号：R737.9[医药卫生—肿瘤]