宝石能谱CT对肺鳞癌分化程度的评估效能  

Efficacy of gemstone spectral computed tomography in evaluating the differentiation degree of lung squamous cell carcinoma

作　　者：刘苗苗[1] 石瑞瑞 马威 LIU Miaomiao;SHI Ruirui;MA Wei(Department of Respiratory Medicine,Puyang People’s Hospital,Puyang 457000,China)

机构地区：[1]濮阳市人民医院呼吸内科,河南濮阳457000 [2]河南大学淮河医院呼吸科

出　　处：《精准医学杂志》2025年第2期178-181,共4页Journal of Precision Medicine

摘　　要：目的探讨宝石能谱CT对肺鳞癌分化程度评估的价值。方法选择2019年2月-2020年2月濮阳市人民医院诊治的86例肺鳞癌患者为研究对象,按照术后病理检查结果分为低分化组(A组)、中分化组(B组)及高分化组(C组)。比较各组患者静动脉期肿瘤宝石能谱CT成像参数及不同病情程度。绘制受试者工作特征(ROC)曲线分析宝石能谱CT成像各参数对肺鳞癌分化程度的评估效能。结果各组患者静脉期宝石能谱CT成像参数比较差异无统计学意义(P>0.05);A组和B组患者动脉期的宝石能谱CT成像中碘浓度(IC)、标准化碘浓度(NIC)、斜率K值和有效原子系数均显著低于C组患者,A组低于B组(t=2.322~14.746,P<0.05);ROC曲线分析显示,低、中、高分化肺鳞癌IC、NIC、斜率K值和有效原子系数四者联合评估肺鳞癌分化程度的特异度和AUC均最高。结论宝石能谱CT各参数对动脉期肺鳞癌分化程度具有较高评估价值。Objective To investigate the value of gemstone spectral CT in evaluating the differentiation degree of lung squamous cell carcinoma.Methods A total of 86 patients with lung squamous cell carcinoma who were diagnosed and treated in Puyang People’s Hospital from February 2019 to February 2020 were enrolled as subjects,and according to the results of postope-rative pathological examination,they were divided into group A(poorly differentiated),group B(moderately differentiated),and group C(highly differentiated).These three groups were compared in terms of gemstone spectral CT imaging parameters and di-sease conditions in the venous and arterial phases.The receiver operating characteristic(ROC)curve was plotted to investigate the efficacy of various gemstone spectral CT imaging parameters in assessing the differentiation degree of lung squamous cell carcinoma.[WTHX]Results There were no significant differences in gemstone spectral CT imaging parameters in the venous phase between groups(P>0.05).Compared with group C,groups A and B had significantly lower gemstone spectral CT imaging parameters of iodine concentration(IC),normalized iodine concentration(NIC),slope K value and effective atomic coefficient in the arterial phase,and group A had significantly lower parameters than group B(t=2.322-14.746,P<0.05).The ROC curve analysis showed that the combination of IC,NIC,slope K value,and effective atomic coefficient had the highest specificity and area under the ROC curve in evaluating the differentiation degree of lung squamous cell carcinoma.Conclusion The parameters of gemstone spectral CT have a relatively high value in assessing the differentiation degree of arterial-phase lung squamous cell carcinoma.

关 键 词：癌 鳞状细胞 肺肿瘤 体层摄影术 X线计算机 诊断 

分 类 号：R730.261[医药卫生—肿瘤] R734.2[医药卫生—临床医学]