纳米金的制备及其应用研究进展  

Research progress on preparation and application of gold nanoparticles

作　　者：何娟 苗延青[1] 刘春叶[1] 张剑 HE Juan;MIAO Yanqing;LIU Chunye;ZHANG Jian(School of Pharmacy,Xi'an Medical University,Xi'an 710021,China)

机构地区：[1]西安医学院药学院,陕西西安710021

出　　处：《化工科技》2025年第2期62-66,共5页Science & Technology in Chemical Industry

基　　金：国家级大学生创新创业训练计划项目(202311840008,121523008);陕西省科技厅社发项目(2023-YBSF-202,2024SF-YBXM-661);西安市科技局高校院所科技人员服务企业项目(24GXFW0082);西安医学院秦创原·科技成果产业化培育项目(21CYH01);西安医学院校内人才项目(2018XNRC03)。

摘　　要：纳米金由于其独特的物理化学性质及良好的生物相容性、制备方法简单、且制成传感器后灵敏度及准确性高,能与多种生物大分子结合且不影响生物活性,近年来纳米金的制备和应用研究取得了显著进展。从物理法、化学法、生物法3个方面对纳米金的制备方法进行了总结,详细叙述了化学法中最经典的柠檬酸钠还原法,其操作流程简便,反应条件温和、成本价格低廉等,成为实验室常用的制备手段。此外,还探讨了纳米金在催化、传感、生物分析及食品检测领域的应用研究进展。Due to its unique physical,chemical properties and good biocompatibility,the preparation method of gold nanoparticles is simple,and the sensitivity and accuracy of the sensor are high.It can combine with a variety of biological macromolecules without affecting its biological activity.Therefore,in recent years,the preparation and application of gold nanoparticles have made significant progress.This article mainly summarizes the preparation methods of nano-gold,from three aspects:physical methods,chemical methods and biological methods.It also elaborates on the most classic sodium citrate reduction method in the chemical methods,which is widely used in laboratories due to its simple operation process,mild reaction conditions,low cost and other advantages.In addition,the application research progress of nano-gold in catalysis,sensing,biological analysis and food detection fields is also discussed.

关 键 词：纳米金 柠檬酸钠还原法 电化学传感器 食品安全检测 

分 类 号：O614.123[理学—无机化学]