角膜塑形镜控制青少年近视的机制研究进展  

Research advance in the mechanisms of myopia control with orthokeratology in adolescent

作　　者：唐仁香 程宇 郑小璐 杨微 傅敏 李炳钦 刘波 TANG Renxiang;CHENG Yu;ZHENG Xiaolu;YANG Wei;FU Min;LI Bingqin;LIU Bo(Department of Ophthalmology,the First Affiliated Hospital of Army Medical University,Chongqing 400038,China)

机构地区：[1]陆军军医大学第一附属医院眼科,重庆市400038

出　　处：《眼科新进展》2025年第5期415-420,共6页Recent Advances in Ophthalmology

基　　金：重庆市科卫联合医学科研项目(编号:2024MSXM016)。

摘　　要：近年来,全球近视患病率居高不下,严重危害青少年的眼部健康。大量研究报道证实角膜塑形镜能控制或延缓近视进展,降低高度近视眼底病变发生率。尽管角膜塑形镜的近视控制效果已得到广泛认可,但其确切作用机制仍不明确,存在多种假设。本文综述了调节、离焦、脉络膜厚度、高阶像差、生物力学等因素在角膜塑形镜控制近视中的作用,探讨这些因素如何共同影响近视的发展。In recent years,the global prevalence of myopia has remained high,seriously endangering the eye health of adolescents.A large number of studies have confirmed that orthokeratology lens can control or delay the progression of myopia and reduce the incidence of fundus lesions in high myopia.Although the efficacy of myopia control with orthokeratology has been widely recognized,its exact mechanism of action is still unclear,and there are many hypotheses.This paper reviews the role of factors such as accommodation,defocus,choroidal thickness,high-order aberrations and biomechanics in myopia control with orthokeratology,and explores how these factors jointly affect the development of myopia.

关 键 词：角膜塑形镜 近视 调节 离焦 脉络膜 高阶像差 生物力学 

分 类 号：R778[医药卫生—眼科]