广泛性焦虑障碍的磁共振成像研究进展  

Research progress in magnetic resonance imaging of generalized anxiety disorder

作　　者：刘冰倩 林冰洁 王梅云[2,4] LIU Bingqian;LIN Bingjie;WANG Meiyun(Department of Medical Imaging,Henan University People's Hospital,Zhengzhou 450003,China;Department of Medical Imaging,Henan Provincial People's Hospital,Zhengzhou 450003,China;Department of Medical Imaging,Zhengzhou University People's Hospital,Zhengzhou 450003,China;Biomedical Research Institute,Henan Academy of Sciences,Zhengzhou 450046,China)

机构地区：[1]河南大学人民医院医学影像科,郑州450003 [2]河南省人民医院医学影像科,郑州450003 [3]郑州大学人民医院医学影像科,郑州450003 [4]河南省科学院生物医学研究所,郑州450046

出　　处：《磁共振成像》2025年第3期98-103,共6页Chinese Journal of Magnetic Resonance Imaging

基　　金：国家自然科学基金项目(编号:82441022、82371934)。

摘　　要：广泛性焦虑障碍(generalized anxiety disorder,GAD)作为最常见的神经精神疾病之一,加重了部分家庭和社会的负担。探索GAD的发病机制、寻找更加精准有效的治疗方法一直是该领域研究者的共同目标。GAD的机制十分复杂,涉及遗传、环境、神经生物学及神经化学等方面。磁共振成像技术凭借其能够从多个层面揭示大脑结构与功能的优势,逐渐成为研究GAD神经机制的重要工具。该技术不仅能提供脑结构、功能连接、白质通路及代谢信息,还能帮助我们深入理解GAD的病理过程,为临床治疗提供有力的理论依据。本文综述了几种磁共振成像技术在GAD中的应用价值及最新研究进展,旨在为进一步揭示GAD的神经机制、推动相关临床研究提供参考和帮助。Generalized anxiety disorder(GAD),as one of the most common neuropsychiatric disorders,exacerbates the burden on some families and society.Exploring the pathogenesis of GAD and finding more precise and effective treatment methods has always been the common goal of researchers in this field.The mechanism of GAD is very complex,involving genetics,environment,neurobiology,and neurochemistry.MRI technology,with its ability to reveal brain structure and function at multiple levels,is gradually becoming an important tool for studying the neuro-mechanisms of generalized anxiety disorder.This technology not only provides information on brain structure,functional connectivity,white matter pathways,and metabolism but also helps us to deeply understand the pathological processes of generalized anxiety disorder,thereby providing a strong theoretical basis for clinical treatment.This article reviews the application value and the latest research progress of several MRI technology in generalized anxiety disorder,aiming to further reveal the neuro-mechanisms of generalized anxiety disorder and promote related clinical research,providing references and assistance.

关 键 词：广泛性焦虑障碍 磁共振成像 医学影像学 神经生物学 研究进展 

分 类 号：R445.2[医药卫生—影像医学与核医学] R749.72[医药卫生—诊断学]