子宫伴奇异形核平滑肌瘤一例  

A Case of Uterine Leiomyoma with Bizarre Nucleus

作　　者：陈淑婉 邓高丕[2] 袁烁[2] CHEN Shu-wan;DENG Gao-pi;YUAN Shuo(Guangzhou University of Chinese Medicine,Guangzhou 510006,China;The First Affiliated Hospital of Guangzhou University of Chinese Medicine,Guangzhou 510405,China)

机构地区：[1]广州中医药大学,510006 [2]广州中医药大学第一附属医院

出　　处：《国际妇产科学杂志》2025年第2期187-190,共4页Journal of International Obstetrics and Gynecology

基　　金：深圳市“医疗卫生三名工程”项目(SZZYSM202106003)。

摘　　要：子宫伴奇异形核平滑肌瘤(uterine leiomyoma with bizarre nucleus,ULBN)是一种罕见的子宫肌瘤亚型,因其与子宫平滑肌肉瘤(leiomyosarcoma,LMS)、延胡索酸水合酶缺陷型子宫平滑肌瘤[fumarate hydratase(FH)-deficient uterine leiomyoma,FH-d UL]拥有相似的病理学表现,故临床不易鉴别,仍依赖排除性诊断。报道广州中医药大学第一附属医院收治的1例以“下腹部肿物突出”为首发症状的ULBN患者。因患者为年轻的育龄期女性,有生育要求,故为其行腹式子宫肌瘤剔除术。通过总结该病的临床特征、分析其术后病理结果和免疫组织化学结果,加深临床医生对此病的认识,提高诊治、鉴别能力。Uterine leiomyoma with bizarre nucleus(ULBN)is a rare subtype of uterine leiomyoma.It is not easy to distinguish clinically because of its similar pathologic manifestations to leiomyosarcoma(LMS)and fumarate hydratase(FH)-deficient uterine leiomyoma(FH-d UL),and the diagnosis of exclusion is still relied upon.This article reports a case of ULBN treated at the First Affiliated Hospital of Guangzhou University of Chinese Medicine,who sought medical advice with a protruding lower abdominal mass as the first symptom.Because the patient was a young woman of childbearing age with fertility requirement,so she underwent laparotomy myomectomy.By summarizing the clinical characteristics of the disease and analyzing its postoperative pathological results and immunohistochemistry,the clinical understanding of the disease will be deepened and the ability to diagnose,treat and distinguish will be improved.

关 键 词：平滑肌瘤 免疫组织化学 诊断 诊断 鉴别 子宫伴奇异形核平滑肌瘤 

分 类 号：R737.33[医药卫生—肿瘤]