生殖系统T淋巴母细胞淋巴瘤一例  

T-Lymphoblastic Lymphoma of Reproductive System: A Case Report

作　　者：王佳丽 马国霞 魏佳 刘思敏 杨永秀[2] WANG Jia-li;MA Guo-xia;WEI Jia;LIU Si-min;YANG Yong-xiu(The First School of Clinical Medicine of Lanzhou University,Lanzhou 730000,China;Department of Obstetrics and Gynecology,The First Hospital of Lanzhou University,Key Laboratory of Gynecological Oncology of Gansu Provincial,Lanzhou 730000,China)

机构地区：[1]兰州大学第一临床医学院,730000 [2]兰州大学第一医院妇产科,甘肃省妇科肿瘤重点实验室

出　　处：《国际妇产科学杂志》2025年第2期195-199,共5页Journal of International Obstetrics and Gynecology

摘　　要：T淋巴母细胞淋巴瘤(T-lymphoblastic lymphoma,T-LBL)是一种罕见且具有高度侵袭性的非霍奇金淋巴瘤(non-Hodgkin lymphoma,NHL),发生于生殖系统者极其罕见。因T-LBL发病率低,且临床表现、实验室检查均缺乏特异性,易造成误诊。报告1例绝经期女性子宫及双侧卵巢T-LBL病例。患者主因腹痛行盆腔磁共振成像(magnetic resonance imaging,MRI)发现盆腔肿物,住院行腹腔镜广泛子宫切除术+双侧输卵管卵巢切除术+部分大网膜切除术,术后病理确诊为子宫及双侧附件T-LBL。因个人因素,患者术后未化疗。术后3个月余被诊断为急性肾衰竭,术后8个月余患者失访。结合此病例讨论并复习相关文献,总结生殖系统淋巴瘤的临床特点、组织病理学表现、诊断、治疗及预后,旨在提高临床医师对该类疾病的认识,为该类疾病的临床诊治提供参考。T-lymphoblastic lymphoma(T-LBL)is a rare and highly aggressive non-Hodgkin lymphoma(NHL).It is extremely rare to occur in the reproductive system.Due to its low incidence and lack of specificity in clinical manifestations and laboratory examinations,it is easy to be misdiagnosed.A case of uterine and bilateral ovary T-LBL in a menopausal female was reported.The patient underwent pelvic magnetic resonance imaging(MRI)for abdominal pain and found pelvic mass.Then the patient underwent extensive laparoscopic hysterectomy,bilateral adnexectomy and partial greater omentectomy.The definite diagnosis of T-LBL was made by the pathology after surgery.Due to personal factors,the patient did not receive chemotherapy after surgery.The patient was diagnosed with acute renal failure more than three months after surgery and the patient was lost to follow-up more than eight months after surgery.The clinical features,histopathological manifestations,diagnosis,treatment and prognosis of lymphomas of the reproductive system were summarized based on this case discussion and review of relevant literature,aim to improve clinical understanding of this disease and provide reference for clinical diagnosis and treatment of this disease.

关 键 词：前体T细胞淋巴母细胞白血病淋巴瘤 淋巴瘤 非霍奇金 生殖器肿瘤 女(雌)性 淋巴瘤 病例报告 

分 类 号：R737.3[医药卫生—肿瘤]