Clinical,endoscopic and histopathological observation of a rare case of esophageal submucosal gland duct adenoma:A case report  

作　　者：Ting Lu Jun-Xing Liu Yin Xia Yan Zhao 

机构地区：[1]Department of Pathology,Nanjing Medical University Affiliated Taizhou People’s Hospital,Jiangsu Taizhou People’s Hospital,Taizhou 225300,Jiangsu Province,China [2]The Second Clinical Medical College,Xuzhou Medical University,Xuzhou 221004,Jiangsu Province,China

出　　处：《World Journal of Gastrointestinal Endoscopy》2025年第4期52-60,共9页世界胃肠内镜杂志(英文)

摘　　要：BACKGROUND Esophageal submucosal gland duct adenoma(ESGDA)is very rare,and easily diagnosed as adenocarcinoma.CASE SUMMARY A 70-year-old man presented with abdominal discomfort and intermittent dull pain during swallowing for 10 days.Digestive endoscopy revealed a polypoid bulge at the esophago-gastric junction,which was resected by endoscopic submucosal dissection(ESD).Routine pathological examination showed intestinal metaplasia of the glandular epithelium on the mucosal surface,with serous tumor-like complex glands in the submucosa which showing significant hyperplasia.This initially diagnosis was early gastric adenocarcinoma.However,we still observed a few points that did not meet the criteria for cancer such as lack of malignant features.Following multidisciplinary discussion and consultation with the experienced specialist pathologists,we finally diagnosed the lesion as a rare ESGDA by further immunohistochemistry.The follow-up examination results for the patient were satisfactory,with no evidence of tumor recurrence.And we summarize the ESGDAs reported in the literature,aiming to enhance understanding of this tumor type.CONCLUSION ESGDA is a benign tumor that can be cured by ESD.Accurate diagnosis can prevent unnecessary extensive therapeutic interventions.

关 键 词：ESOPHAGUS Submucosal gland DUCT ADENOMA Case report 

分 类 号：R735.1[医药卫生—肿瘤]