Application of aggregation-induced emission materials in gastrointestinal diseases  

作　　者：Yi-Rong Li Gang Wang Wen-Ting He Tao Liu 

机构地区：[1]School of Basic Medical Sciences,Lanzhou University,Lanzhou 730000,Gansu Province,China [2]Digestive System Tumor Prevention and Treatment and Translational Medicine Engineering Innovation Center of Lanzhou University,Lanzhou University,Lanzhou 730000,Gansu Province,China [3]Digestive System Tumor Translational Medicine Engineering Research Center of Gansu Province,Lanzhou University,Lanzhou 730000,Gansu Province,China [4]Gansu Provincial Key Laboratory of Environmental Oncology,Lanzhou University,Lanzhou 730000,Gansu Province,China [5]The Second Hospital&Clinical Medical School,Lanzhou University,Lanzhou 730030,Gansu Province,China

出　　处：《World Journal of Gastroenterology》2025年第16期5-15,共11页世界胃肠病学杂志(英文)

基　　金：Supported by The Science and Technology Program of Gansu Province,No.23JRRA1015.

摘　　要：Aggregation-induced emission(AIE)is a phenomenon characterized by certain fluorescent molecules that exhibit weak or no luminescence in solution but demonstrate significantly enhanced luminescence upon aggregation.Accordingly,AIE materials have successfully addressed the limitations associated with aggregation-caused quenching effects and have made significant progress in the application of various fields of medicine in recent years.At present,the application of AIE materials in gastrointestinal(GI)diseases is mainly in GI imaging,diagnosis and treatment.In this review,we summarize the applications of AIE materials in GI pathogens and GI diseases,including inflammatory bowel disease and GI tumors,and outline combined treatment methods of AIE materials in GI tumor therapy.

关 键 词：Aggregation-induced emission luminogens Gastrointestinal pathogens Inflammatory bowel disease Gastrointestinal cancer Photodynamic therapy 

分 类 号：R57[医药卫生—消化系统]