Is global interest in fasting,intermittent fasting and the liver shifting?  

作　　者：Athanasios Tselebis Lina Zabuliene Ioannis Ilias 

机构地区：[1]Department of Psychiatry,"Sotiria"General Chest Diseases Hospital,Athens GR-11527,Greece [2]Faculty of Medicine,Vilnius University,Vilnius LT-03101,Lithuania [3]Department of Endocrinology,Hippocration General Hospital,Athens GR-11527,Greece

出　　处：《World Journal of Hepatology》2025年第4期151-154,共4页世界肝病学杂志(英文)

摘　　要：A recent article highlighted the hepatic benefits of intermittent fasting,particularly during Ramadan.However,the rising use of glucagon-like peptide-1(GLP-1)/glucose-dependent insulinotropic polypeptide(GIP)receptor agonists(RAs)is altering public behavior,leading to decreased interest in diet and exercise.With a focus on hepatic health,we analyzed global search trends using Google Trends™data from January 1,2022 to December 31,2024,focusing on the keywords"fasting","intermittent fasting","diet","nutrition","liver",Semaglutide("Ozempic"™,the most widely known GLP-1 RA)and Tirzepatide("Mounjaro"™,a newer dual GLP-1 and GIP RA).Search interest for"intermittent fasting"and"diet"showed a significant decline over time(Spearman's rho:-0.582 and-0.605,respectively,both P<0.001),while interest in"fasting"and"nutrition"remained stable.Search interest for Semaglutide,Tirzepatide,"fasting and liver","diet and liver"and Semaglutide and"liver"increased(Spearman's rho:+0.914,+0.936,+0.369,+0.297 and+0.808,respectively,all P<0.001).These findings suggest a trend of shifting away from traditional dieting toward broader health concerns,likely influenced by the increasing use of GLP-1/GIP RAs.

关 键 词：Intermittent fasting Glucagon-like peptide-1 receptor agonists Glucosedependent insulinotropic polypeptide receptor agonists Weight management Diet trends HEPATIC Public health behavior 

分 类 号：R57[医药卫生—消化系统]