溃疡性结肠炎患者结直肠息肉复发的相关危险因素分析  

To analyze the related risk factors of colorectal polyp recurrence in patients with ulcerative colitis

作　　者：王子奇 谭诗云[1] WANG Ziqi;TAN Shiyun(Department of Gastroenterology,Renmin Hospital of Wuhan University,Wuhan 430060,China)

机构地区：[1]武汉大学人民医院消化内科,湖北武汉430060

出　　处：《胃肠病学和肝病学杂志》2025年第3期373-376,共4页Chinese Journal of Gastroenterology and Hepatology

摘　　要：目的探讨溃疡性结肠炎(ulcerative colitis,UC)患者合并结直肠息肉复发的相关危险因素。方法选取2019年1月至2020年12月就诊于武汉大学人民医院既往明确诊断为UC合并结直肠息肉的患者89例(病例组)及该期间正常肠黏膜合并息肉患者92例的相关资料进行回顾性分析。分别比较病例组与对照组性别、年龄、内镜下息肉特点、病理类型及切除后复发等情况,探究分析UC合并结直肠息肉复发的相关危险因素。结果单因素及多因素Logistic回归分析显示,吸烟史、病程时间、息肉数量是UC患者息肉复发的危险因素。结论应密切监测既往吸烟史、病程≥5年及息肉数量≥3枚的UC患者,并在早期内镜检查中进行积极干预,以降低UC相关结直肠癌的发生风险,改善其长期预后。Objective To investigate the risk factors of colorectal polyps recurrence in patients with ulcerative colitis(UC).Methods From Jan.2019 to Dec.2020,the relevant data of 89 patients with UC complicated with colorectal polyps(case group)and 92 patients with normal intestinal mucosa complicated with polyps in Renmin Hospital of Wuhan University were retrospectively analyzed.The gender,age,endoscopic polyp characteristics,pathological type and recurrence after resection were compared between the case group and the control group,and the risk factors related to the recurrence of UC combined with colorectal polyps were analyzed.Results Univariate and multivariate Logistic regression analysis showed that smoking history,duration of disease and the number of diseased polyps were the risk factors of polyp recurrence in UC patients.Conclusion UC patients with smoking history,disease duration≥5 years and number of polyps≥3 should be closely monitored,and active intervention should be carried out in early endoscopy to reduce the risk of UC-associated colorectal cancer and improve their long-term prognosis.

关 键 词：溃疡性结肠炎 结直肠息肉 溃疡性结肠炎相关结直肠癌 结直肠早癌 

分 类 号：R574.62[医药卫生—消化系统]