颞下颌关节中成体间充质干细胞的研究进展  

Research progress on the adult mesenchymal stem cells in the temporomandibular joint

作　　者：龚吴仪 米晓晖[1] 李永明 GONG Wuyi;MI Xiaohui;LI Yongming(Shanghai Engineering Research Center of Tooth Restoration and Regeneration&Tongji Research Institute of Stomatology&Department of Orthodontics,Shanghai Tongji Stomatological Hospital and Dental School,Tongji University,Shanghai 200072,China)

机构地区：[1]上海市同济口腔医院正畸科,同济大学口腔医学院,上海牙组织修复与再生工程技术研究中心,同济大学口腔医学研究所,上海200072

出　　处：《口腔颌面外科杂志》2025年第2期145-148,共4页Journal of Oral and Maxillofacial Surgery

基　　金：国家自然科学基金(81970921)。

摘　　要：颞下颌关节(temporomandibular joint,TMJ)是下颌骨各项生理运动的结构基础,但其自我修复能力较差,病理状态导致的软骨与骨缺损难以再生。成体间充质干细胞(mesenchymal stem cells,MSCs)凭借其成软骨与成骨多向分化能力成为TMJ组织再生修复的研究热点。本文将聚焦TMJ中存在的成体MSCs,并对其近年的研究进展进行综述。The temporomandibular joint(TMJ)is the structural basis of mandibular movements,but its poor self-repairing ability makes the cartilage and bone defects hard to regenerate under pathological conditions.Adult mesenchymal stem cells(MSCs)have become a research hotspot in the tissue repairing of the TMJ due to their ability to differentiate toward chondrocytes and osteocytes.This article will focus on adult MSCs in the TMJ and review their recent research progress.

关 键 词：颞下颌关节 成体间充质干细胞 祖细胞 

分 类 号：R782[医药卫生—口腔医学]