Tracing global progress:two decades of age-related macular degeneration research  

作　　者：Li-Yun Yuan Liang-Pin Li Xia Hua Xiao-Yong Yuan 

机构地区：[1]School of Medicine,Nankai University,Tianjin 300071,China [2]Tianjin Key Laboratory of Ophthalmology and Visual Science,Tianjin Eye Institute,Tianjin Eye Hospital,Tianjin 300020,China [3]Tianjin Aier Eye Hospital,Tianjin University,Tianjin 300190,China

出　　处：《International Journal of Ophthalmology(English edition)》2025年第5期925-936,共12页国际眼科杂志(英文版)

基　　金：Supported by the National Natural Science Foundation of China(No.82371033);the Tianjin Natural Science Foundation(No.21JCZDJC01250);the Tianjin Key Medical Discipline(Specialty)Construction Project(No.TJYXZDXK-016A).

摘　　要：AIM:To conduct a comprehensive bibliometric analysis of age-related macular degeneration(AMD)research from 2002 to 2022,identifying key contributing countries,institutions,authors,journals,and research hotspots to inform future research directions.METHODS:Publications related to AMD were retrieved from the Web of Science Core Collection(WoSCC)database for the period January 1,2002,to December 31,2022.The search was limited to English-language articles and reviews.Bibliometric analysis was performed using Microsoft Excel 2021 for data management and annual publication analysis.Visualization and network analyses were conducted using VOSviewer,CiteSpace,and the Bibliometrix package in R.Collaboration networks among countries,institutions,authors,and journals were mapped.Keywords were analyzed for co-occurrence to identify research hotspots.Metrics such as H-index,total link strength(TLS),and citation counts were used to assess impact.RESULTS:A total of 16715 publications were analyzed,showing a consistent increase in AMD research output over the past 20y,peaking at 1445 publications in 2021.The United States was the leading contributor with 31.8%of total publications,followed by China and the United Kingdom.The University of Melbourne emerged as the most productive institution with the highest TLS,indicating strong international collaborations.Professor Frank G.Holz was identified as the most influential author based on H-index and publication count.Investigative Ophthalmology&Visual Science was the most prolific journal and had the highest citation impact.Keyword co-occurrence analysis revealed four main research clusters:pathogenesis,therapy,epidemiology,and diagnosis.Emerging research hotspots included anti-vascular endothelial growth factor(VEGF)therapies,optical coherence tomography angiography,and artificial intelligence(AI)applications in diagnosis.CONCLUSION:The bibliometric analysis highlights significant growth and collaborative efforts in AMD research globally.Key contributors have advanced understanding

关 键 词：age-related macular degeneration bibliometric analysis research trends collaboration networks research hotspots 

分 类 号：R774.1[医药卫生—眼科]