三种角膜屈光术式矫正维吾尔族中、低度近视患者的临床疗效  

Clinical efficacy of three corneal refractive surgery techniques in the correction of moderate and low myopia in Uyghur patients

作　　者：何青松 王琴 周奇志 HE Qingsong;WANG Qin;ZHOU Qizhi(Department of Refractive Surgery,Urumqi Aier Adiya Ophthalmology Hospital,Urumqi 830001,CHINA)

机构地区：[1]乌鲁木齐爱尔阿迪娅眼科医院屈光手术科,新疆830001 [2]爱尔眼科重庆眼视光眼科医院屈光手术科

出　　处：《江苏医药》2025年第3期264-267,共4页Jiangsu Medical Journal

基　　金：新疆维吾尔自治区非公立医疗机构协会临床科研专项资金项目(FG201912)。

摘　　要：目的比较三种角膜屈光术式矫正维吾尔族中、低度近视患者的临床疗效。方法根据眼部检查结果和患者自愿选择术式,维吾尔族中、低度近视患者34例(64眼)分为飞秒激光辅助准分子激光原位角膜磨镶术(FS-LASIK)组(10例,20眼)、经上皮准分子激光角膜切削术(T-PRK)组(12例,22眼)和小切口角膜基质透镜取出术(SMILE)组(12例,22眼)。比较三组术后3、6个月的残余等效球镜(SE)、裸眼视力(UCVA)、最佳矫正视力(BCVA)以及安全指数和有效指数。比较三组术后3、6个月0.8≤UCVA<1.0和UCVA≥1.0的眼数。结果术后3个月,SMILE组UCVA优于FS-LASIK组(P<0.05);三组残余SE、BCVA、安全指数及有效指数比较均无统计学差异(P>0.05)。术后6个月,FS-LASIK组BCVA优于SMILE组,安全指数优于T-PRK组和SMILE组(P<0.05);而三组残余SE、UCVA和有效指数比较无统计学差异(P>0.05)。64眼术后3、6个月UCVA均≥0.8;术后3个月,SMILE组UCVA≥1.0的眼数比例高于FS-LASIK组和T-PRK组(P<0.05)。结论三种角膜屈光术式矫正维吾尔族中、低度近视患者均取得良好的临床效果,其中FS-LASIK的有效性和安全性最高。Objective To compare the clinical efficacy of three corneal refractive surgery techniques in the correction of moderate and low myopia in Uyghur patients.Methods Based on the results of ocular examinations and patient preferences,34 Uyghur patients(64 eyes)with moderate to low myopia were divided into three groups of femtosecond-assisted laser in situ keratomileusis(FS-LASIK)with 10 cases(20 eyes),transepithelial photorefractive keratectomy(T-PRK)with 12 cases(22 eyes)and small incision lenticule extraction(SMILE)with 12 cases(22 eyes).Residual spherical equivalent(SE),uncorrected visual acuity(UCVA),best corrected visual acuity(BCVA),safety index and effective index at 3 and 6 months after surgery were compared among the three groups.Additionally,the proportion of the eyes achieving 0.8≤UCVA<1.0 and UCVA≥1.0 at 3 and 6 months after surgery was compared among the three groups.Results Three months after surgery,UCVA of SMILE group was better than that of FS-LASIK group(P<0.05),and there were no significant differences in residual SE,BCVA,safety index and effective index among the three groups(P>0.05).Six months after surgery,BCVA of FS-LASIK group was better than that of SMILE group,and safety index of FS-LASIK group was better than that of groups of T-PRK and SMILE(P<0.05),while there were no significant differences in residual SE,UCVA and effective index among the three groups(P>0.05).Sixty-four eyes had a UCVA of at least 0.8 at both 3 and 6 months postoperatively.The proportion of the eyes with a UCVA of at least 1.0 in SMILE group was more than that in groups of FS-LASIK and T-PRK(P<0.05).Conclusion Three corneal refractive surgery techniques to correct moderate and low degree myopia in Uyghur patients have achieved good clinical outcomes,and FS-LASIK has the highest effectiveness and safety.

关 键 词：飞秒激光辅助准分子激光原位角膜磨镶术 经上皮准分子激光角膜切削术 小切口角膜基质透镜取出术 近视 

分 类 号：R778[医药卫生—眼科]