子午流注温和灸联合四磨汤对急性白血病化疗患者便秘的影响  

Effect of mild moxibustion based on the theory of midnight-noon ebb-flow combined with Simo decoction on constipation in patients with acute leukemia undergoing chemotherapy

作　　者：黄瑞萍[1] 董珂丽 苏继亮 戴文丽 HUANG Ruiping;DONG Keli;SU Jiliang;DAI Wenli(Department of Hematology,the First Affiliated Hospital of Nanchang University,Nanchang 330000,Jiangxi,China)

机构地区：[1]南昌大学第一附属医院血液科,南昌330000

出　　处：《癌症进展》2025年第8期919-923,共5页Oncology Progress

基　　金：江西省中医药管理局科技计划项目(2023B0204)。

摘　　要：目的目的探讨子午流注温和灸联合四磨汤对急性白血病(AL)化疗患者便秘的影响。方法方法采用随机数字表法将100例化疗期间发生便秘的AL患者分为对照组(n=50)和联合组(n=50),对照组患者接受常规治疗及健康宣教,联合组患者在对照组的基础上接受子午流注温和灸联合四磨汤治疗。比较两组患者的排便情况、便秘情况[便秘评分系统(CCS)、Bristol粪便性状评分量表(BSFS)]、负性情绪[焦虑自评量表(SAS)、抑郁自评量表(SDS)]、生活质量[便秘患者生存质量自评量表(PAC-QOL)]及便秘复发情况。结果结果治疗后,联合组患者首次排便时间、每次排便时间、大便形态复常时间均明显短于对照组,差异均有统计学意义(P﹤0.01)。治疗后,两组患者CCS、BSFS、SAS、SDS评分及PAC-QOL各维度评分均低于本组治疗前,联合组患者CCS、BSFS、SAS、SDS评分及PAC-QOL各维度评分均低于对照组,差异均有统计学意义(P﹤0.05)。联合组患者随访1个月的便秘复发率为0%,与对照组患者的10%比较,差异无统计学意义(P﹥0.05)。结论结论子午流注温和灸联合四磨汤能显著促进AL化疗患者排便,改善便秘情况及负性情绪,提高生活质量。Objective To explore the effect of mild moxibustion based on the theory of midnight-noon ebb-flow com-bined with Simo decoction on constipation in patients with acute leukemia(AL)undergoing chemotherapy.Method A total of 100 AL patients with constipation during chemotherapy were randomly divided into control group(n=50)and combined group(n=50)according to random number table method.Patients in the control group received conventional treatment and health education,patients in the combined group received mild moxibustion based on the theory of mid-night-noon ebb-flow combined with Simo decoction treatment on the basis of the control group.The defecation situation,constipation status[Cleveland clinic constipation score(CCS),Bristol stool form scale(BSFS)],negative emotions[self-rating anxiety scale(SAS),self-rating depression scale(SDS)],quality of life[patient assessment of constipation quality of life questionnaire(PAC-QOL)],and recurrence of constipation were compared between the two groups.Result After treatment,the first defecation time,defecation time per session,and time for normal stool form in the combined group were significantly shorter than those in the control group,and the differences were statistically significant(P<0.01).After treatment,the scores of CCS,BSFS,SAS,SDS and the dimensional scores of PAC-QOL in both groups were lower than those before treatment,the scores of CCS,BSFS,SAS,SDS and the dimensional scores of PAC-QOL in combined group were lower than those in control group,and the differences were statistically significant(P<0.05).The recurrence rate of constipation in the combined group was 0%after 1-month follow-up,which was not statistically different compared to 10%in the control group(P>0.05).Conclusion Mild moxibustion based on the theory of midnight-noon ebb-flow com-bined with Simo decoction can significantly promote defecation in AL patients undergoing chemotherapy,improve consti-pation and negative emotions,and enhance the quality of life.

关 键 词：子午流注温和灸 四磨汤 急性白血病 化疗 便秘 

分 类 号：R733.71[医药卫生—肿瘤]