肠道菌群及其代谢物与卒中后认知损害  

Gut microbiota and its metabolites and post-stroke cognitive impairment

作　　者：刘炳男 高迎 张金彪[2] Liu Bingnan;Gao Ying;Zhang Jinbiao(School of Clinical Medicine,Shandong Second Medical University,Weifang 261053,China;Department of Neurology,Weihai Municipal Hospital,Weihai 264200,China)

机构地区：[1]山东第二医科大学临床医学院,潍坊261053 [2]威海市立医院神经内科,威海264200

出　　处：《国际脑血管病杂志》2024年第11期852-856,共5页International Journal of Cerebrovascular Diseases

摘　　要：卒中后认知损害(post-stroke cognitive impairment,PSCI)是在卒中发病后3~6个月内表现出的认知损害甚至痴呆的一类临床综合征。肠道菌群及其代谢物已被证实与PSCI相关。文章对肠道菌群及其代谢物与PSCI的相关性进行了综述,为PSCI的早期干预及治疗提供新思路。Post-stroke cognitive impairment(PSCI)is a clinical syndrome characterized by cognitive impairment and even dementia that occurs within 3-6 months after the onset of stroke.The gut microbiota and its metabolites have been confirmed to be associated with PSCI.This article reviews associations of gut microbiota and its metabolites with PSCI,providing new ideas for early intervention and treatment of PSCI.

关 键 词：卒中 认知功能障碍 胃肠道微生物群 丁酸盐(酯)类 甲胺类 脂肪酸类 挥发性 

分 类 号：R743.3[医药卫生—神经病学与精神病学]