3D-CT影像技术辅助胸腔镜肺段切除术治疗非小细胞肺癌的疗效及预后分析  

Efficacy and prognostic analysis of 3D-CT imaging technology-assisted thoracoscopic segmentectomy in the treatment of non-small cell lung cancer

作　　者：唐兴 白国艳 蒋玉涵 沈晶[1] 张清[1] 伍建林[1] TANG Xing;BAI Guoyan;JIANG Yuhan;SHEN Jing;ZHANG Qing;WU Jianlin(Department of Medical Imaging,Zhongshan Hospital Affiliated to Dalian University,Dalian 116001,China;Department of Radiology,the First Affiliated Hospital of Air Force Medical University,Xi’an 710032,China;Department of Laboratory Medicine,Shaanxi Provincial People’s Hospital,Xi’an 710068,China)

机构地区：[1]大连大学附属中山医院医学影像科,辽宁大连116001 [2]空军军医大学第一附属医院放射科,陕西西安710032 [3]陕西省人民医院检验科,陕西西安710068

出　　处：《机器人外科学杂志(中英文)》2025年第4期649-654,共6页Chinese Journal of Robotic Surgery

基　　金：国家自然科学基金(82071911)。

摘　　要：目的:探究3D-CT影像技术辅助胸腔镜肺段切除术治疗非小细胞肺癌的疗效及预后。方法:回顾性分析2020年7月—2021年7月大连大学附属中山医院收治的106例非小细胞肺癌患者的临床资料,按治疗方法分为3D-CT影像技术辅助组(57例,实施3D-CT影像技术辅助胸腔镜肺段切除术)和常规组(49例,实施胸腔镜肺段切除术)。比较两组疗效、手术指标与术后恢复指标、肺功能指标、并发症及预后(随访3年)的差异。结果:3D-CT影像技术辅助组疗效优于常规组(P<0.05)。与常规组比较,3D-CT影像技术辅助组术中出血量、引流量及手术、拔管、住院时间均更低(P<0.05)。相较于术前,两组术后15 d每分钟最大通气量、用力肺活量、肺一氧化碳弥散量均降低(P<0.05),但与常规组比较,3D-CT影像技术辅助组均更高(P<0.05)。3D-CT影像技术辅助组术后并发症总发生率低于常规组(P<0.05)。所有患者经随访3年后,KM生存分析显示,3D-CT影像技术辅助组生存状况显著优于常规组(P<0.05)。结论:3D-CT影像技术辅助胸腔镜肺段切除术治疗非小细胞肺癌具有较好的疗效,可有效提高肺功能,减少术后并发症发生率,促进术后恢复,改善预后。Objective:To investigate the efficacy and prognosis of 3D-CT imaging technology-assisted thoracoscopic segmentectomy in the treatment of non-small cell lung cancer(NSCLC).Methods:Clinical data of 106 NSCLC patients who were treated at Zhongshan Hospital Affiliated to Dalian University from July 2020 to July 2021 were retrospectively analyzed.Patients were divided into the 3D-CT group(n=57,3D-CT imaging technology-assisted thoracoscopic segmentectomy)and the conventional group(n=49,standard thoracoscopic segmentectomy)based on different treatment methods.Comparisons were made regarding therapeutic efficacy,surgical and postoperative recovery indicators,pulmonary function parameters,complications,and prognosis(3-year follow-up).Results:The 3D-CT group showed superior therapeutic efficacy compared to the conventional group(P<0.05).Significantly reduced intraoperative blood loss,drainage volume,operative time,tube removal time,and length of hospital stay were found in the 3DCT group compared to the conventional group(P<0.05).At 15 days after surgery,the two groups both showed decreased maximum voluntary ventilation,forced vital capacity,and diffusion capacity of the lung for carbon monoxide compared to preoperative levels(P<0.05).However,these parameters were significantly higher in the 3D-CTgroup than those in the conventional group(P<0.05).The total incidence of complications was lower in the 3D-CT group than that in the conventional group(P<0.05).Kaplan-Meier survival analysis after 3-year follow-up revealed significantly better survival outcomes in the 3D-CT group than that in the conventional group(P<0.05).Conclusion:3D-CT imaging technology-assisted thoracoscopic segmentectomy can achieve favorable efficacy in treating NSCLC,it can effectively improve pulmonary function,reduce postoperative complications,accelerate patients’recovery after surgery,and enhance prognosis.

关 键 词：非小细胞肺癌 胸腔镜手术 肺段切除术 3D-CT影像技术 

分 类 号：R734.2[医药卫生—肿瘤]