山莨菪碱联合奥曲肽用于粘连性肠梗阻的疗效观察  

Clinical Efficacy of Anisodamine Combined with Octreotide in Treatment of Adhesive Intestinal Obstruction

作　　者：张倩 ZHANG Qian(Third Affiliated Hospital,Nanyang Medical College,Nanyang,Henan 473000)

机构地区：[1]南阳医学高等专科学校第三附属医院,河南南阳473000

出　　处：《中国肛肠病杂志》2025年第3期23-25,共3页Chinese Journal of Coloproctology

摘　　要：目的:探讨山莨菪碱联合奥曲肽用于粘连性肠梗阻患者的临床效果。方法:选取2019年1月至2022年12月,本院收治68例粘连性肠梗阻患者,随机分为观察组和对照组,每组各34例。对照组给予奥曲肽治疗,观察组采用山莨菪碱联合奥曲肽治疗,观察比较2组患者症状消失时间、胃肠功能、炎症因子水平及不良反应等。结果:观察组症状消失时间短于对照组(P<0.05),胃肠功能指标优于对照组(P<0.05),炎性因子水平低于对照组(P<0.05)。观察组不良反应发生率为17.65%,略高于对照组的14.71%,但差异无统计学意义(P>0.05)。结论:粘连性肠梗阻患者采用山莨菪碱联合奥曲肽治疗,能快速缓解患者症状,恢复胃肠功能,且患者炎症反应较轻,值得推广。Objective To investigate the clinical efficacy of anisodamine combined with octreotide in patients with adhesive intestinal obstruction.Methods From January 2019 to December 2022,total 68 patients with adhesive intestinal obstruction were selected and randomly divided into the observation group and the control group,with 34 cases in each group.The control group was treated with octreotide,and the observation group was given anisodamine combined with octreotide.Symptom disappearance time,gastrointestinal function,inflammatory factor levels and adverse reactions of the two groups were observed and compared.Results The symptom disappearance time of the observation group was shorter than that of the control group(P<0.05),the gastrointestinal function index was better than that of the control group(P<0.05),the inflammatory factor levels were lower than those of the control group(P<0.05).The incidence of adverse reactions in the observation group was 17.65%,slightly higher than that in the control group(14.71%),but the difference was not statistically significant(P>0.05).Conclusion Anisodamine combined with octreotide can quickly relieve symptoms and restore gastrointestinal function in patients with adhesive intestinal obstruction,and the inflammatory reaction of patients is relatively mild,which is worth promoting.

关 键 词：粘连性肠梗阻 山莨菪碱 奥曲肽 疗效 

分 类 号：R574.2[医药卫生—消化系统]