CT小肠造影对小儿溃疡性结肠炎临床活动分期的应用价值  

The clinical application value of CT enterography in clinical activity and endoscopic scores of pediatric ulcerative colitis

作　　者：吴朔春[1] 孙雪峰[1] 王文燕[2] 杨梅[1] WU Shuo-chun;SUN Xue-feng;WANG Wen-yan;YANG Mei(Department of Radiology,Children’s Hospital Affiliated to Capital Institute of Pediatrics,Beijing 100020,China;Department of Medical Imaging,the Second Hospital of Hebei Medical University,Shijiazhuang 050000,China)

机构地区：[1]首都儿科研究所附属儿童医院放射科,北京100020 [2]河北医科大学第二医院医学影像科,河北石家庄050000

出　　处：《中国临床医学影像杂志》2025年第4期275-278,284,共5页Journal of China Clinic Medical Imaging

基　　金：首都儿科研究所所级课题资助(项目编号FZYJ-2025-23)。

摘　　要：目的:通过CT小肠造影(CTE)评估小儿溃疡性结肠炎(UC)患儿肠道状态,并探讨CTE影像与小儿UC临床活动分期及内镜评分的相关性。方法:收集2015年1月—2022年10月我院53例临床确诊小儿UC患儿的临床、内镜及CTE影像学资料。采用Fisher精确概率检验及Spearman相关性分析法判断CTE评估与小儿UC活动度分期及内镜评分结果的相关性。结果:小儿UC轻~重度活动期CTE影像表现为肠壁分层强化多见、肠腔狭窄、肠腔黏膜多呈卵石征及肛瘘、盆腔积液出现比例高。Spearman相关性分析法结果显示CTE影像表现中病变肠壁强化方式、肠腔黏膜形态、肛瘘出现比例高,与小儿UC的内镜评分之间具有显著正相关性。结论:CTE的病变肠壁强化方式、肠腔黏膜形态、肠腔狭窄及肛瘘、盆腔积液出现比例参数指标对判别小儿UC活动分期有重要参考价值。内镜评分与小儿UC的CTE表现呈正相关。Objective:To evaluate the intestinal status of children with pediatric ulcerative colitis(UC)by using CT enterography(CTE)and to explore the correlation between CTE imaging and clinical activity stages and endoscopic scores of pediatric UC.Methods:Clinical,endoscopic,and CTE imaging data of 53 children clinically diagnosed with ulcerative colitis and admitted to the Department of Pediatric Gastroenterology of our hospital from January 2015 to October 2022 were collected.The Fisher’s exact test and Spearman correlation analysis were used to analyze the correlation between CTE evaluation and the results of pediatric UC activity staging and endoscopic scoring.Results:The CTE images of pediatric UC during the mild to severe active phase showed that the proportion of patients with layered wall enhancement of the intestine,intestinal stenosis,intestinal mucosa presenting eggshell sign,and anal fistula and pelvic effusion was higher.The results of Spearman correlation analysis showed that there was a significant positive correlation between the high proportion of intestinal wall enhancement,intestinal mucosal morphology,anal fistula appearance,and the endoscopic scoring of pediatric UC in CTE imaging,which had a significant statistical significance.Conclusion:The manifestations of CTE imaging,such as intestinal wall enhancement,intestinal mucosal morphology,intestinal stenosis,anal fistula,and pelvic effusion,are of great reference value for distinguishing pediatric UC activity staging.Endoscopic scoring is positively correlated with CTE imaging of pediatric UC.

关 键 词：结肠炎 溃疡性 体层摄影术 螺旋计算机 

分 类 号：R574.62[医药卫生—消化系统] R814.42[医药卫生—内科学]