1990—2019年全球部分国家10岁以下儿童膳食铁缺乏疾病负担分析  

Analysis of burden in children under 10 years old of dietary iron deficiency among some countries in the world from 1990 to 2019

作　　者：陈可彬 王婷婷[1] 孙梦婷 罗曼君 阮霄睿 秦家碧[1,2] Chen Kebin;Wang Tingting;Sun Mengting;Luo Manjun;Ruan Xiaorui;Qin Jiabi(Department of Epidemiology and Health Statistics,Xiangya School of Public Health,Central South University,ChangSha 410013,China;Department of Maternal,Child and Adolescent Health,School of Public Health,Kunming Medical University,Kunming 650500,China)

机构地区：[1]中南大学湘雅公共卫生学院流行病与卫生统计学系,长沙410013 [2]昆明医科大学公共卫生学院儿少卫生与妇幼保健学系,昆明650500

出　　处：《中华预防医学杂志》2025年第4期468-473,共6页Chinese Journal of Preventive Medicine

基　　金：国家自然科学基金项目(82473644,82073653);湖南省杰出青年基金项目(2022JJ10087)。

摘　　要：基于2019年全球疾病负担(GBD2019)数据库,描述全球154个“一带一路”倡议(BRI)国家膳食铁缺乏的疾病负担现状;通过Joinpoint回归模型分析疾病负担时间变化趋势;使用皮尔森相关与局部加权回归探究疾病负担与社会人口指数(SDI)之间的关联性;选用斜度指数和集中指数评估健康不平等;使用前沿分析探索疾病前沿,评价指标主要为患病率与伤残调整寿命年。结果显示,1990—2019年分别有117和125个BRI国家10岁以下儿童膳食铁缺乏年龄标准化患病率和年龄标准化伤残调整寿命年率呈现下降趋势,且2019年疾病负担与SDI均呈负相关关系(R=-0.80,P<0.001)。同时,1990年、2019年的斜度指数分别为-936(95%CI:-1006,-806)、-1128(95%CI:-1256,-999),1990年、2019年的集中指数分别为-0.24(95%CI:-0.28,-0.20)、-0.35(95%CI:-0.39,-0.30)。此外,部分国家离前沿边界的有效差异较大。Based on the Global Burden of Disease(GBD)2019,this study characterized the burden of dietary iron deficiency across 154 countries participating in the Belt and Road Initiative(BRI).A joinpoint regression model was employed to assess temporal trends in disease burden.Pearson correlation analysis and locally weighted regression were utilized to investigate the relationship between burden and the socio-demographic index(SDI).Slope indices and concentration indices were calculated to evaluate health inequalities,while frontier analysis explored disease burden benchmarks.Key metrics included prevalence and disability-adjusted life years(DALYs).Results revealed downward trends in age-standardized prevalence rates and age-standardized DALYs rates of dietary iron deficiency among children under 10 years old in 117 and 125 BRI countries,respectively,from 1990 to 2019.A significant negative correlation was observed between disease burden and SDI in 2019(R=-0.80,P<0.001).The slope indices decreased from-936(95%CI:-1006,-806)in 1990 to-1128(95%CI:-1256,-999)in 2019,while the concentration indices declined from-0.24(95%CI:-0.28,-0.20)to-0.35(95%CI:-0.39,-0.30)during the same period.Frontier analysis further identified substantial gaps between observed outcomes and optimal performance thresholds in several countries.

关 键 词：儿童 膳食铁缺乏 疾病负担 时间趋势 健康不平等 前沿分析 

分 类 号：R153.2[医药卫生—营养与食品卫生学]