重视生物力学在眼病发病机制及诊疗中的作用  

The critical role of biomechanics in the management and pathogenesis of ocular diseases

作　　者：王雁[1] 霍炎 Wang Yan;Huo Yan(Tianjin Eye Hospital,Nankai University Affiliated Eye Hospital,Clinical College of Ophthalmology of Tianjin Medical University,Tianjin Eye Institute,Tianjin Key Laboratory of Ophthalmology and Visual Science,Tianjin 300020,China)

机构地区：[1]天津市眼科医院,南开大学附属眼科医院,天津医科大学眼科临床学院,天津市眼科研究所,天津市眼科学与视觉科学重点实验室,天津300020

出　　处：《中华眼科杂志》2025年第4期241-244,共4页Chinese Journal of Ophthalmology

基　　金：国家重点研发计划(2022YFC2404502);国家自然科学基金面上项目(82271118);天津市科技计划(21JCZDJC01190);天津市卫生健康科技项目(TJWJ2022XK036);天津市医学重点学科(专科)建设项目(TJYXZDXK-016A)。

摘　　要：生物力学是一门研究生物体与力学之间内在关系的交叉学科,其在疾病的发生和发展及诊疗中发挥重要作用,与眼部的生长发育以及病变及进展、损伤及修复等机制和相关诊疗工作密切相关。本文从眼科临床对生物力学重视不足,生物力学可成为解决眼科诊疗难题的关键突破口,需要重视并逐步构建融入生物力学的新型诊疗范式3个方面,论述了生物力学在眼病发病机制及诊疗中的重要性及亟待解决的问题,提出应重视生物力学的作用,旨在为眼科临床开展相关工作提供指导意见。Biomechanics is an interdisciplinary field that studies the intrinsic relationship between biology and mechanics.It plays a crucial role in the occurrence,development,diagnosis,and treatment of diseases.In ophthalmology,biomechanics is particularly relevant to the mechanisms of ocular growth,development,pathological changes,injury repair,disease progression,and the diagnostic and therapeutic approaches associated with ocular diseases.This article addresses three key aspects:the insufficient attention given to biomechanics in ophthalmology,the potential of biomechanics as a critical breakthrough in overcoming clinical challenges in ophthalmic diagnosis and treatment,and the need to gradually establish a new diagnostic and therapeutic paradigm that incorporates biomechanics.We emphasize the importance of biomechanics in the pathogenesis and diagnosis of ocular diseases,highlight the urgent issues,and advocate for greater focus on the role of biomechanics to guide clinical practice.

关 键 词：生物力学现象 眼疾病 早期诊断 精准医学 跨学科学习 眼科学 力学生物学 

分 类 号：R77[医药卫生—眼科]