充分认识角膜生物力学特性在青光眼诊疗中的参考价值  

Unveiling the pivotal role of corneal biomechanical parameters in glaucoma diagnosis and therapy

作　　者：才瑜[1] 魏雅慧 王雁[2] Cai Yu;Wei Yahui;Wang Yan(Department of Ophthalmology,Peking University First Hospital,Beijing 100034,China;Tianjin Eye Hospital,Nankai University Affiliated Eye Hospital,Clinical College of Ophthalmology of Tianjin Medical University,Tianjin Eye Institute,Tianjin Key Laboratory of Ophthalmology and Visual Science,Tianjin 300020,China)

机构地区：[1]北京大学第一医院眼科,北京100034 [2]天津市眼科医院,南开大学附属眼科医院,天津医科大学眼科临床学院,天津市眼科研究所,天津市眼科学与视觉科学重点实验室,天津300020

出　　处：《中华眼科杂志》2025年第4期245-250,共6页Chinese Journal of Ophthalmology

摘　　要：青光眼是全球首位不可逆性致盲眼病,发病机制尚不十分明确。随着生物力学检测技术发展,活体眼球生物力学研究成为可能,越来越多研究者开始关注角膜生物力学特性与青光眼发生和发展的关系。本文从掌握角膜生物力学概念和检测技术、关注角膜生物力学与青光眼的关系、深入探讨角膜生物力学的影响因素、辩证理解角膜生物力学校正眼压在青光眼诊疗中的应用4个方面进行阐述,提出应充分认识角膜生物力学特性在青光眼诊疗中的参考价值,以期与眼科同道共同开展相关研究,进一步促进青光眼诊疗水平提高。Glaucoma stands as the leading cause of irreversible blindness globally,yet its pathogenesis remains incompletely understood.With the advancements in biomechanical detection technologies,in-vivo biomechanical research on the eyeball has become feasible.An increasing number of researchers have turned their attention to the intricate relationship between the biomechanical properties of the cornea and the onset and progression of glaucoma.This article delves into four crucial aspects:grasping the concepts and detection techniques of corneal biomechanics,exploring the correlation between corneal biomechanics and glaucoma,investigating the influencing factors of corneal biomechanics in glaucoma cases,and understanding the application of corneal biomechanics-corrected intraocular pressure in glaucoma diagnosis and treatment.It emphasizes the need to comprehensively recognize the reference value of corneal biomechanical parameters in glaucoma diagnosis and treatment.The authors aim to collaborate with fellow ophthalmologists in related research,with the ultimate goal of enhancing the diagnostic and therapeutic standards for glaucoma.

关 键 词：青光眼 角膜 生物力学现象 精准医学 早期诊断 

分 类 号：R775[医药卫生—眼科]